Biochemical Factors associated with Breast Cancer in Bangladeshi Women

  • DAS Hussain Dept of Biochemistry, Shaheed Monsur Ali Medical College and Dhaka
  • S Ahmed Dept of Biochemistry, Popular Medical College, Dhaka
  • M Hoque Dept of Biochemistry, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka
  • SMR Rabbi Laser Aesthetics, Dhanmondi, Dhaka
  • S Masood Dept of Physiology, BSMMU, Dhaka
  • T Shafi Dept of Biochemistry, Medical College for Women and Hospital, Dhaka
  • T Parvia Dept of Cardiology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka
  • HS Chaudhury Dept of Biochemistry & Molecular Biology, International Medical College, Gazipur
Keywords: Breast cancer, Lipid profile, Estrogen, Progesterone

Abstract

Breast Cancer is the commonest maligrancy in woment. A study was carried out in the Department of Biochemistry, Dhaka Medical College to investigate some of the biochemical features that are associated with breast cancer occurring in Bangladeshi women. Thirty diagnosed breast cancer patients and thirty healthy women were selected. A questionnaire was used for collecting information regarding age, family history, physical activity and exercise, BMI, diet, smoking, alcohol abuse, addiction, details of menstrual and obstetric history, breast-feeding, parity, use of contraceptives and HRT. Blood samples were collected and tested for fasting lipid profiles, serum estrogen and progesterone. The study has revealed that high levels of serum total cholesterol (P<0.05), TAG (P<0.05), LDL-C (P<0.05) and low level of serum and HDL-C (P<0.05) were found to be associated with breast cancer. The study further reveals that blood levels of estrogen (P<0.05) and progesterone (P<0.05) were found to be lower than that of the controls.

DOI: http://dx.doi.org/10.3329/bjmb.v6i2.17644

Bangladesh J Med Biochem 2013; 6(2): 58-62

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Abstract
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Published
2014-01-13
How to Cite
Hussain, D., Ahmed, S., Hoque, M., Rabbi, S., Masood, S., Shafi, T., Parvia, T., & Chaudhury, H. (2014). Biochemical Factors associated with Breast Cancer in Bangladeshi Women. Bangladesh Journal of Medical Biochemistry, 6(2), 58-62. https://doi.org/10.3329/bjmb.v6i2.17644
Section
Original Articles