Metabolic Syndrome and Insulin resistance: Etiopathegenesis and influencing factors

  • AK Al-Mahmood Dept of Biochemistry, Ibn Sina Medical College, Dhaka
  • SF Afrin Dept of Biochemistry, Ibn Sina Medical College, Dhaka
  • N Hoque Dept of Biochemistry, Faridpur Medical College, Faridpur
Keywords: Metabolic Syndrome, insulin receptor, insulin resistance

Abstract

Metabolic syndrome and insulin resistance has been the subject of much debate over the last two decades. Its pathophysiologycal basis, however, still remains to be clearly understood. Both genetic and environmental factors have been implicated in its pathogenesis. Mutation of genes encoding signal transduction molecules of insulin and acquired factors like aging, diets, physical activity, obesity and related molecular changes, dyslipidemia, hypertension and smoking were proposed by many groups. This review examined both acquired and genetic factors and discussed model of hormone-receptor-postreceptor interactions to explore the molecular basis of insulin resistance.

DOI: http://dx.doi.org/10.3329/bjmb.v4i2.13773

Bangladesh J Med Biochem 2011; 4(2): 26-31

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Abstract
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Published
2013-02-13
How to Cite
Al-Mahmood, A., Afrin, S., & Hoque, N. (2013). Metabolic Syndrome and Insulin resistance: Etiopathegenesis and influencing factors. Bangladesh Journal of Medical Biochemistry, 4(2), 26-31. https://doi.org/10.3329/bjmb.v4i2.13773
Section
Review Articles