<i>Clostridium perfringens</i>: Sporulation, Spore Resistance and Germination

Authors

  • I-Hsiu Huang Department of Biomedical Sciences, College of Veterinary Medicine & Department of Microbiology, College of Science, Oregon State University, Corvallis, OR97331, USA
  • Deepa Raju Department of Biomedical Sciences, College of Veterinary Medicine & Department of Microbiology, College of Science, Oregon State University, Corvallis, OR97331, USA
  • Daniel Paredes-Sabja Department of Biomedical Sciences, College of Veterinary Medicine & Department of Microbiology, College of Science, Oregon State University, Corvallis, OR97331, USA
  • Mahfuzur R Sarker Department of Biomedical Sciences, College of Veterinary Medicine & Department of Microbiology, College of Science, Oregon State University, Corvallis, OR97331, USA

DOI:

https://doi.org/10.3329/bjm.v24i1.1229

Keywords:

Clostridium perfringens, Endospore, Small, acid soluble spore protein (SASP), Heat resistance, Germination

Abstract

Clostridium perfringens are Gram-positive, endospore-forming, anaerobic bacteria with the ability to cause enteric diseases both in human and domesticated animals. As one of the leading cause of food-borne illness in the United States, certain C. perfringens type A isolates exert their action through the production of C. perfringens enterotoxin (CPE), which is expressed only during spore formation. In addition, C. perfringens spores are highly resistant to heat and other environmental factors. Since genome sequences of three C. perfringens strains have been annotated and made public, efforts have been made towards understanding the initiation of sporulation and identifying the key differences between Clostridium and Bacillus sporulation phosphorelay. Small, acid soluble spore proteins (SASPs) have been shown to be required for resistance of C. perfringens spores to heat. Work is also underway to identify nutrient signals required for C. perfringens spore germination.

Keywords: Clostridium perfringens, Endospore, Small, acid soluble spore protein (SASP), Heat resistance, Germination

DOI: http://dx.doi.org/10.3329/bjm.v24i1.1229

Bangladesh J Microbiol, Volume 24, Number 1, June 2007, pp 1-8

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How to Cite

Huang, I.-H., Raju, D., Paredes-Sabja, D., & Sarker, M. R. (2008). <i>Clostridium perfringens</i>: Sporulation, Spore Resistance and Germination. Bangladesh Journal of Microbiology, 24(1), 1–8. https://doi.org/10.3329/bjm.v24i1.1229

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Section

Review Article