Association of Serum Vitamin D level with in-hospital Outcome in Patients with Acute Myocardial infarction

Authors

  • Khandaker Abu Rubaiyat Junior Consultant, Department of Cardiology, M Abdur Rahim Medical College Hospital, Dinajpur, Bangladesh
  • Abdul Wadud Chowdhury Professor & Head of the Department, Department of Cardiology, Dhaka Medical College Hospital, Dhaka, Bangladesh
  • Mohsin Ahmed Associate Professor, Department of Cardiology, National Institute of Cardiovascular Diseases, Dhaka, Bangladesh
  • Md Gaffar Amin Assistant Professor, Department of Cardiology, Dhaka Medical College, Dhaka, Bangladesh
  • ATM Mahfuzul Hoque Assistant Professor, Department of Cardiology, Dhaka Medical College, Dhaka, Bangladesh
  • Kazi Nazrul Islam Assistant Professor, Department of Cardiology, Dhaka Medical College, Dhaka, Bangladesh
  • Chowdhury Md Kudrat E Khuda Assistant Professor, Department of Cardiology, National Institute of Cardiovascular Diseases, Dhaka, Bangladesh
  • ABM Imam Hosen Junior Consultant (Cardiology), Jhalakati Sadar Hospital, Jhalakati, Bangladesh
  • Md Mozammel Haque Assistant Professor, Department of Cardiology, National Institute of Cardiovascular Diseases, Dhaka, Bangladesh

DOI:

https://doi.org/10.3329/bhj.v37i2.63132

Keywords:

AMI, Serum vitamin D, Adverse in-hospital outcome

Abstract

Objective: Vitamin D deficiency is emerging as a new risk factor for various cardiovascular events. Several studies have been done to find out association of vitamin D level with CAD with varying Results. Very few studies, however, have investigated the association between serum vitamin D levels and clinical outcomes in ACS patients thus far. The  Objective of this study was to assess the association between serum vitamin D levels and in-hospital complications of AMI patients in Department of Cardiology, Dhaka Medical College Hospital (DMCH), Dhaka.

Methods: This was a cross-sectional observational study. We measured serum vitamin D level in AMI (STEMI and NSTEMI) patients (n=198) admitted in Department of Cardiology, DMCH. Patients with normal vitamin D level (e”30 ng/ml) were considered as Group I and patients with low serum vitamin D level (<30 ng/ml) were considered as Group II; and in-hospital complications were evaluated.

Results: The study showed that 51% of study subjects of AMI had in-hospital complications; 71.1% patients with low vitamin D level had adverse in-hospital outcome whereas 14.3% patients with normal vitamin D level had AMI complications which was statistically significant (p<0.001). Heart failure and arrhythmias were the most frequently observed complications. The Results of the study demonstrates that the association between low vitamin D level and in-hospital complications after AMI remains statistically significant (p<0.001).

Conclusions: Low serum vitamin D level is independently associated with a higher frequency of several in-hospital adverse clinical events including mortality after acute myocardial infarction (STEMI and NSTEMI). Whether low vitamin D levels represent a risk marker or a risk factor in ACS remains to be elucidated.

Bangladesh Heart Journal 2022; 37(2): 89-98

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Published

2022-12-28

How to Cite

Rubaiyat, K. A. ., Chowdhury, A. W. ., Ahmed, M. ., Amin, M. G. ., Hoque, A. M. ., Islam, K. N. ., Khuda, C. M. K. E. ., Hosen, A. I. ., & Haque, M. M. . (2022). Association of Serum Vitamin D level with in-hospital Outcome in Patients with Acute Myocardial infarction. Bangladesh Heart Journal, 37(2), 89–98. https://doi.org/10.3329/bhj.v37i2.63132

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Section

Original Articles