Clinicopathological profile & outcome of critically ill patients suffering from Dengue: Single Centre Experience during COVID Pandemic

Authors

  • Kaniz Fatema Associate Professor, Dept of CCM, BIRDEM General Hospital, Dhaka.
  • Alimul Haque Medical Officer, ICU, Islami Bank Central Hospital Kakrail, Dhaka.
  • ASM Areef Ahsan Professor & Head, Dept of CCM, BIRDEM General Hospital, Dhaka.
  • Fatema Ahmed Associate Professor, Dept of CCM, BIRDEM General Hospital, Dhaka.
  • Debasish Kumar Saha Assistant Professor, Dept of CCM, BIRDEM General Hospital, Dhaka.
  • Madhurima Saha Assistant Professor, Dept of CCM, BIRDEM General Hospital, Dhaka.
  • Suraiya Nazneen Assistant Professor, Dept of CCM, BIRDEM General Hospital, Dhaka.
  • Rozina Sultana Junior Consultant, Dept of CCM, BIRDEM General Hospital, Dhaka
  • Ishrat Jahan Registrar, Dept of CCM, BIRDEM General Hospital, Dhaka.
  • Taslima Begum SMO, Dept of CCM, BIRDEM General Hospital, Dhaka
  • Khandaker Sabbir Ahmed In-charge ICU, Islami Bank Central Hospital Kakrail, Dhaka

DOI:

https://doi.org/10.3329/bccj.v11i2.69162

Keywords:

Dengue,, Intensive Care Unit,, Critically ill patients.

Abstract

Introduction: Dengue is endemic in our country contributing significantly in morbidity & mortality. This study was conducted to observe the clinic-pathological profile, presentation & outcome of critically ill dengue patients who required Intensive Care Unit admission.

Methods: This observational study was conducted in ICU of a tertiary care hospital in Dhaka city from July 2021 to September 2021. Laboratory confirmed cases of Dengue patients admitted in ICU were included in the study.

Results: Total patients were 40 with equal male-female distribution. Mean age of the patients was 39.17 ± 13.83 years with most of them (70%) in age group of 18-40 years. Direct admission through Emergency Room (42.5%) was more than transfer-in from indoor of same hospital & other hospitals (35% & 22.5% respectively). There were multiple reasons for ICU admission including hypotension (commonest reason), breathlessness, diarrhoea, abdominal distension, altered level of consciousness etc. Only 13 (32.5%) patients had co-morbidities like DM, HTN etc, and mean age of them was significantly higher than patients without co-morbidities (50.3 ± 13.31, vs 32.23 ± 6.88). Biochemical parameters showed that TWBC count was normal in most patients (n=27, 67.5%), thrombocytopenia was present in 35 (87.5%) patients during admission, hypocalcaemia was present in most patients (90%), liver enzymes were raised in most patients (87.5% & 95% respectively for AST & ALT) and three patients had AKI. Twenty percent patients needed vasopressor support for shock & 5% needed mechanical ventilator support for respiratory failure. Clinical condition was improved in 38 patients & most of them (82.5%) were transferred out from ICU within 6 days. Only two among forty patients expired despite resuscitative efforts. There was no significant difference in the biochemical parameters between survivors & non-survivors.

Conclusion: As dengue specific treatment is not yet available, early recognition of the critically ill patients and immediate supportive treatment along with close monitoring in Intensive Care Unit is life-saving for the patients.

Bangladesh Crit Care J September 2023; 11 (2): 68-74

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Published

2023-10-04

How to Cite

Kaniz Fatema, Alimul Haque, ASM Areef Ahsan, Ahmed, F. ., Debasish Kumar Saha, Madhurima Saha, Suraiya Nazneen, Rozina Sultana, Ishrat Jahan, Taslima Begum, & Khandaker Sabbir Ahmed. (2023). Clinicopathological profile & outcome of critically ill patients suffering from Dengue: Single Centre Experience during COVID Pandemic. Bangladesh Critical Care Journal, 11(2), 68–74. https://doi.org/10.3329/bccj.v11i2.69162

Issue

Vol. 11 No. 2 (2023)

Section

Original Articles

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