Brain death diagnosis in adult for potential cadaveric organ donation in Bangladesh

  • Fatema Ahmed Assistant Professor, Dept. of Critical Care Medicine, BIRDEM General Hospital, Dhaka
  • ASM Areef Ahsan Professor and head, Dept. of Critical Care Medicine, BIRDEM General Hospital, Dhaka
  • Mohammad Omar Faruq Professor, Dept. of Critical Care Medicine, Ibn Sina Hospital, Dhanmondi , Dhaka
  • Kaniz Fatema Consultant, Dept. of Critical Care Medicine, BIRDEM General Hospital, Dhaka
  • Debasish Kumar Saha Registrar, Dept. of Critical Care Medicine, BIRDEM General Hospital, Dhaka
  • Madhurima Saha Registrar, Dept. of Critical Care Medicine, BIRDEM General Hospital, Dhaka
  • Suraiya Nazneen Registrar, Dept. of Critical Care Medicine, BIRDEM General Hospital, Dhaka
  • Md Shah Zaman Consultant. Uttara Crescent Hospital, Dhaka
  • Md Rezaul Karim Honorary medical officer. Dept. of Critical Care Medicine, BIRDEM General Hospital, Dhaka
  • Khan Md Shafikul Alam Resident medical officer. ICU of Islami bank central Hospital, Dhaka
  • Tarikul Hamid Medical officer. Dept. of Critical Care Medicine, BIRDEM General Hospital, Dhaka
Keywords: Brain death, Intensive Care Unit, cadaveric transplantation

Abstract

Aim: The objectives of this study was (i) To increase knowledge of the epidemiological and clinical features of patients diagnosed with brain death for potential cadaveric organ donation (ii) To determine the compliance of guidelines brain death based on neurological criteria (iii) To analyse process of clinical decision making regarding continuation of life support after brain death diagnosis.

Materials and Method: A prospective observational study was carried out in a 12 bed adult ICU of a tertiary care hospital with neurosurgery services in Bangladesh over a period of 2 years from January 2015 to December2016. All patients admitted during this period were scrutinized for identification of brain death and impending brain death. They were analyzed for causes of brain death, diagnosis of brain death, and the use of ancillary testing. Potential for organ donation was also kept in mind.

Results: During the study period, total 1387 patients were admitted into the study ICU and there were 329 deaths. And out of them 69 were diagnosed as brain death. The main causes of brain death were intracerebral haemorrhage (32/69, 46%), followed by ischemic stroke (11/69, 16%), subarachnoid haemorrhage (11/69, 12%), traumatic brain injury (8/69, 12%) and brain tumor and CNS infection. The diagnosis of brain death was made in 33 (47%) cases in the first 48 hours and 23 (33%) cases in 48-96 hours of ICU admission. With the exception of two cases, all study patients had GCS score ? 8 (97%). Brain death was diagnosed according to American Academy of Neurology (AAN) 2010 guidelines. Only two cases Electroencephalography was done for family request. All life-sustaining measures were withdrawn in 67 (97%) cases with consent of family.

Conclusion: There is no scarcity of brain death cases in our country according to our study. We need to promote and popularize the cadaveric organ transplant along with living donor transplantation.

Bangladesh Crit Care J March 2017; 5(1): 48-52

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Author Biography

Fatema Ahmed, Assistant Professor, Dept. of Critical Care Medicine, BIRDEM General Hospital, Dhaka


Published
2017-05-11
How to Cite
Ahmed, F., Ahsan, A., Faruq, M. O., Fatema, K., Saha, D., Saha, M., Nazneen, S., Zaman, M. S., Karim, M. R., Alam, K., & Hamid, T. (2017). Brain death diagnosis in adult for potential cadaveric organ donation in Bangladesh. Bangladesh Critical Care Journal, 5(1), 48-52. https://doi.org/10.3329/bccj.v5i1.32543
Section
Original Articles