Prolonged Pyrexia due to Hemophaghocytic Lymphohistiocytosis

  • Farzana Shumy Medical Officer, Department of Internal Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbagh, Dhaka 1000
  • Tanvir Ahmed Resident, Department of Oncology, Bangabandhu Sheikh Mujib Medical University, Shahbagh, Dhaka 1000
  • Ahmad Mursel Anam Chief Resident, ICU, Square Hospitals Ltd. 18/F, BU Qazi Nuruzzaman Sarak (West Panthapath), Dhaka 1205
  • Abed Hussain Khan Medical Officer, Department of Internal Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbagh, Dhaka 1000
  • Mohammad Ferdous Ur Rahaman Assistant Professor, Department of Internal Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbagh, Dhaka 1000
  • Quazi Mamtaz Uddin Ahmed Associate Professor, Department of Internal Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbagh, Dhaka 1000
  • MA Jalil Chowdhury Professor & Chairman, Department of Internal Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbagh, Dhaka 1000
Keywords: Haemophaghocytic lymphohistiocytosis, Fever, Pancytopenia

Abstract

Haemophaghocytic lymphohistiocytosis (HLH) is an uncommon illness in adults. It is rare but common clinical features like lymphadenopathy, hepatosplenomegaly, fever are presentation of many different familiar clinical illness, make it a diagnostic challenge. Here, we present a case of a previously healthy young boy presented with fever and other features like hepatosplenomegaly, pancytopenia, markedly elevated serum ferritin, Lactate dehydrogenase, triglyceride, low fibrinogen, persistent hyponatremia and finally detectable Haemophagocytosis in his bone marrow. Unfortunately, diagnosis was delayed around 4 month after his initial presentation and he succumbed to his disease. This case highlights common clinical features and diagnostic difficulties have to face in making confirmed diagnosis of HLH.

Bangladesh Crit Care J September 2015; 3 (2): 77-78

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Author Biography

Farzana Shumy, Medical Officer, Department of Internal Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbagh, Dhaka 1000


Published
2015-09-22
How to Cite
Shumy, F., Ahmed, T., Anam, A., Khan, A., Rahaman, M. F., Ahmed, Q., & Chowdhury, M. (2015). Prolonged Pyrexia due to Hemophaghocytic Lymphohistiocytosis. Bangladesh Critical Care Journal, 3(2), 77-78. https://doi.org/10.3329/bccj.v3i2.25118
Section
Case Reports