Serum Procalcitonin Guided Antibiotic Therapy in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Authors

  • Rawshan Arra Khanam MD (Chest diseases), Specialist, Dept. of Medicine, United Hospital Ltd
  • Md Ashraful Haque Diploma in Anaesthesia, Specialist, Intensive Care Unit, United Hospital Ltd, Dhaka
  • Mohammad Omar Faruq Professor of Dept of CCM, BIRDEM General Hospital, Dhaka

DOI:

https://doi.org/10.3329/bccj.v3i2.25114

Keywords:

AECOPD, PCT

Abstract

Chronic obstructive pulmonary disease (COPD) is a preventable and treatable, but progressive disease. Hospital admissions of patients with COPD are frequently due to acute exacerbations of COPD (AECOPD). AECOPD are very common, affecting about 20% of COPD patients. The bacterial infection plays an important role in the exacerbation of COPD patients. In addition, recent studies using molecular diagnostics indicate that a substantial proportion of AECOPD are associated with viral infection. Accurate methods to differentiate viral and bacterial respiratory infections to allow targeted antibiotic therapy would be beneficial. Acute phase reactants are capable of demonstrating the inflammation; however, they cannot be employed to make a difference between bacterial and nonbacterial causes of the inflammation. Recently, measurement of procalcitonin (PCT) levels appears to be useful in order to minimize this problem.

Bangladesh Crit Care J September 2015; 3 (2): 67-70

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Author Biography

Rawshan Arra Khanam, MD (Chest diseases), Specialist, Dept. of Medicine, United Hospital Ltd



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Published

2015-09-22

How to Cite

Khanam, R. A., Haque, M. A., & Faruq, M. O. (2015). Serum Procalcitonin Guided Antibiotic Therapy in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease. Bangladesh Critical Care Journal, 3(2), 67–70. https://doi.org/10.3329/bccj.v3i2.25114

Issue

Section

Review Articles