HELLP syndrome: An experience of treating with plasma exchange

  • Shahzadi Sayeeda Tun Nessa Clinical Staff, Intensive Care Unit, SQUARE Hospital Limited, 18/F, BU Qazi Nuruzzaman Sarak (West Panthapath), Dhaka 1205
  • Mohammd Mufizul Islam Polash Clinical Staff, Intensive Care Unit, SQUARE Hospital Limited, 18/F, BU Qazi Nuruzzaman Sarak (West Panthapath), Dhaka 1205
  • Md Motiul Islam Clinical Staff, Intensive Care Unit, SQUARE Hospital Limited, 18/F, BU Qazi Nuruzzaman Sarak (West Panthapath), Dhaka 1205
  • Ahmad Mursel Anam Chief Resident, Intensive Care Unit, SQUARE Hospital Limited, 18/F, BU Qazi Nuruzzaman Sarak (West Panthapath), Dhaka 1205
  • Muhammad Mahbubul Rahman Bhuiyan Clinical Staff, Intensive Care Unit, SQUARE Hospital Limited, 18/F, BU Qazi Nuruzzaman Sarak (West Panthapath), Dhaka 1205
Keywords: HELLP, Preeclampsia, Therapeutic Plasma Exchange

Abstract

In the spectrum of patient with severe pre-eclampsia, there is a potentially lethal complication called HELLP syndrome( haemolysis, elevated liver enzyme and low platelet count).1 The pathogenesis of HELLP syndrome is unclear. If it is a form of severe preeclampsia, it likely originates from aberrant placental development and function. As an independent entity, it has been attributed to abnormal placentation, similar to preeclampsia, but with greater hepatic inflammation and greater activation of the coagulation system than in preeclampsia.2,3,4 HELLP develops in approximately 0.5 to 0.9 percent of all pregnancies and in 10 to 20 percent of women with severe preeclampsia/eclampsia.5 Maternal mortality rate in HELLP syndrome is variable(1-23%) due to severity of disease, delayed diagnosis and presence of multi-organ involvement.6,7 So the recognition of HELLP syndrome and an aggressive multidisciplinary approach are required for the improvement of meternofoetal prognosis.

DOI: http://dx.doi.org/10.3329/bccj.v1i2.17204

Bangladesh Crit Care J September 2013; 1 (2): 102-103

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Abstract
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PDF
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Published
2013-12-01
How to Cite
Nessa, S., Polash, M., Islam, M., Anam, A., & Bhuiyan, M. (2013). HELLP syndrome: An experience of treating with plasma exchange. Bangladesh Critical Care Journal, 1(2), 102-103. https://doi.org/10.3329/bccj.v1i2.17204
Section
Case Reports