Outcome of Different Treatment Modalities in Non-caseating Granulomatous Mastitis: A Narrative Review

Authors

  • Shamima Nasrin Assistant professor, Department of Surgery, Anwer Khan Modern Medical College, Dhaka
  • Mir Rasekh Alam Ovi Consultant Surgery, General hospital Narayangonj, Dhaka
  • Abdus Salam Arif Professor and Head, Department of Surgery, Anwer Khan Modern Medical College, Dhaka
  • Md Jahid Hasan Consultant, Pi Research Consultancy Center, Dhaka

DOI:

https://doi.org/10.3329/akmmcj.v13i1.64729

Keywords:

Granulomatous mastitis, non-caseating,

Abstract

Granulomatous mastitis (GM) is a benign inflammatory condition of breast disease that affects women of childbearing age with a history of breastfeeding. The rarity and complex pathophysiology make the diagnosis and management quite dilemmatic for clinicians. This review explored the available treatment options for the disease condition in light of the recent literature. Surgery alone, intervention with or without steroids, antibiotic therapy, abscess drainage, methotrexate therapy, and antibiotics are widely used in different settings. However, surgery (with or without steroids) showed a higher recovery rate along with a lower recurrence rate. Steroid therapy is promising, but its use is limited due to the higher number of recurrences. In addition, the use of methotrexate showed an increased remission rate, but the toxicity profile was still high. However, treatment outcome mostly depends on the severity of the disease and individual physical status, and therefore, a comprehensive evaluation of the patients is crucial. This review recommended the formulation of a standard guideline for uniform management of granulomatous mastitis conditions in our country.

AKMMC J 2022; 13(1) : 47-51

Downloads

Download data is not yet available.
Abstract
132
PDF
134

Downloads

Published

2021-12-28

How to Cite

Nasrin, S., Alam Ovi, M. R., Arif, A. S. ., & Hasan, M. J. . (2021). Outcome of Different Treatment Modalities in Non-caseating Granulomatous Mastitis: A Narrative Review. Anwer Khan Modern Medical College Journal, 13(1), 47–51. https://doi.org/10.3329/akmmcj.v13i1.64729

Issue

Section

Review Articles