Management of Anemia in Cancer Patients

  • Ehteshamul Hoque Professor, Department of Oncology, Anwer Khan Modern Medical College Hospital
  • Shanaz Karim Associate Professor, Department of Transfusion Medicine Dhaka Medical College Hospital
  • Mazharul Hoque Professor, Department of Transfusion Medicine, Dhaka Medical College Hospital
  • Anika Nawer Hoque Lecturer, Department of Microbiology, Anwer Khan Modern Medical College
  • Israq Elahi Lecturer, Department of Physiology, Anwer Khan Modern Medical College
Keywords: Anaemia, Cancer, Erythropoiesis-Stimulating Agents

Abstract

Anemia is a frequent complication in cancer patients. Cancer-related anemia adversely affects quality of life and is associated with reduced overall survival. Reasons for anemia in cancer patients are decreased production of RBCs resulting from nutritional deficiencies; insufficient production of RBCs because of the presence of chronic disease; Cancer promotes inflammatory cytokine production, which suppresses erythropoiesis and erythropoietin (EPO) production; bone marrow infiltration by the tumor or bone marrow suppression resulting from anticancer treatment such as surgery, chemotherapy, or radiotherapy; and increased loss of RBCs caused by blood loss from the tumor, surgery, or hemolysis. Correction of anemia can be achieved by different methods.Treatment is aimed at increasing the oxygen-carrying capacity of the blood, reducing fatigue, and improving the patient's overall quality of life. Erythropoiesisstimulating agents, iron supplementation, and red blood cell transfusions have all been recommended in different settings.

Anwer Khan Modern Medical College Journal Vol. 11, No. 1: Jan 2020, P 66-72

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Abstract
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PDF
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Published
2020-02-27
How to Cite
Hoque, E., Karim, S., Hoque, M., Hoque, A. N., & Elahi, I. (2020). Management of Anemia in Cancer Patients. Anwer Khan Modern Medical College Journal, 11(1), 66-72. https://doi.org/10.3329/akmmcj.v11i1.45670
Section
Review Articles