Effect of Vitamin A on Lung Function Test in patient with Chronic Bronchial Asthma

Authors

  • M Obaidulla Ibne Ali Associate Professor & Head, Department of Physiology, Rajshahi Medical College, Rajshahi
  • Nur E Atia Junior Consultant, Gynae & Obs Mohanpur UHC, Rajshahi
  • Tohorul Islam Junior Consultant, Department of Radiology & Imaging Sadar Hospital, Chapinawabgonj
  • MN Islam Assistant Professor, Department of Medicine Rajshahi Medical College, Rajshahi
  • PM Basak Assistant Professor, Department of Medicine Rajshahi Medical College, Rajshahi
  • CK Das Associate Professor, Department of Community Medicine Rajshahi Medical College, Rajshahi

DOI:

https://doi.org/10.3329/taj.v27i1.37602

Abstract

In chronic bronchial asthma inflammation may be accompanied by intensive air flow limitation. Endogenous oxidants produced by overactive inflammatory cells destroy airway epithelium which slough into bronchial lumen and thus aggravates asthma. When oxidant overwhelm anti-oxidants, tissue injury and disease results. It is observed that decrease level of anti-oxidants in the lungs is a feature of chronic bronchial asthma and that there is a marked decrease of these levels during acute asthmatic attacks. These observations highlight the positive correlation between anti-oxidant therapy in asthmatic patients. The study was carried out to observe the changes in lung function in patients with chronic bronchial asthma both before and after supplementation of anti-oxidant vitamin A. Pulmonary function variables such as FVE, FEV1, FEV1/FVC%and PEFR were measured by spirometer in patients with chronic bronchial asthma both before and three month after supplementation of vitamin A 10,000 I.U orally daily. The mean FVC, FEV1, FEV1/FVC% and PEFR following vitamin A was unchanged significantly (P<0.001) than the pre supplementation values in patients with chronic bronchial asthma. This study reveals that no improvement of pulmonary functions occur after supplementation of anti-oxidant vitamin A in chronic bronchial asthma patients.

TAJ 2014; 27(1): 10-13

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Published

2018-11-28

How to Cite

Ali, M. O. I., Atia, N. E., Islam, T., Islam, M., Basak, P., & Das, C. (2018). Effect of Vitamin A on Lung Function Test in patient with Chronic Bronchial Asthma. TAJ: Journal of Teachers Association, 27(1), 10–13. https://doi.org/10.3329/taj.v27i1.37602

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Section

Original Articles