TY - JOUR AU - Hasan, Md Kamrul AU - Kabir, Abul Kalam Lutful AU - Mistry, Sabyasachy PY - 2010/08/12 Y2 - 2024/03/28 TI - Chemical and Biological Investigation of Leaves of Polygonum plebejum JF - Stamford Journal of Pharmaceutical Sciences JA - S.J. Pharm. Sci VL - 2 IS - 2 SE - Research Articles DO - 10.3329/sjps.v2i2.5826 UR - https://www.banglajol.info/index.php/SJPS/article/view/5826 SP - 66-71 AB - The cytotoxic and antimicrobial activity of methanol crude extract and column fractions of the extract of the<br />leaves of <em>P. plebejum</em> were examined by brine shrimp lethality bioassay and disc diffusion method<br />respectively. The extracts showed significant cytotoxic as well as antimicrobial activities. Silica gel column<br />chromatography of methanol extract of <em>P. plebejum </em>afforded a steroid. The structure was elucidated on the<br />basis of spectral analysis, including <sup>1</sup>H NMR and <sup>13</sup>C NMR and also by comparing with data in the literature.<br />&nbsp;<br /><strong>Key words: </strong><em>Polygonum plebejum</em>; <em>Polygonaceae</em>; Stigmasterol; Cytotoxicity.<br /><br />DOI: 10.3329/sjps.v2i2.5826<br /><br /><em>Stamford Journal of Pharmaceutical Sciences</em> Vol.2(2) 2009: 66-71<br /> ER -