TY - JOUR AU - Choudhary, K AU - Singh, M AU - Pillai, U AU - Shekhawat, N S PY - 2010/08/12 Y2 - 2024/03/29 TI - Antibacterial Screening and Phytochemical investigation of bark extracts of Acacia jacquemontii Benth. JF - Stamford Journal of Pharmaceutical Sciences JA - S.J. Pharm. Sci VL - 2 IS - 2 SE - Research Articles DO - 10.3329/sjps.v2i2.2384 UR - https://www.banglajol.info/index.php/SJPS/article/view/2384 SP - 21-26 AB - <em>Acacia&nbsp; jacquemontii </em>was&nbsp; assessed&nbsp; for&nbsp; active&nbsp; principles&nbsp; to&nbsp; ascertain&nbsp; the&nbsp; rationale&nbsp; for&nbsp; its&nbsp; use&nbsp; in&nbsp; traditional <br />medicine. Preliminary phytochemical screening of the stem bark extracts showed that it possessed the active <br />principles - alkaloids, glycosides, saponins, terpenoids and tannins. The antimicrobial activity of the extracts <br />was assayed against pathogenic strains of Bacillus cereus, <em>Bacillus pumilus</em>, <em>Escherichia coli</em>, <em>Pseudomonas <br />aeruginosa</em>, <em>Staphylococcus aureus</em>, <em>S. pyrogenes</em>, and <em>Candida albcans</em> using&nbsp; the agar diffusion method. <br />The plant extract exhibited antimicrobial activity against all the test microorganisms. <em>B. cereus</em> and <em>B. pumilus </em><br />were the most susceptible to the plant extract while <em>Candida albicans</em> was the most resistant. The minimum <br />inhibitory&nbsp; concentration&nbsp; of&nbsp; the&nbsp; stem&nbsp; bark&nbsp; extract&nbsp; of&nbsp; the&nbsp; plant&nbsp; ranged&nbsp; between&nbsp; 30&nbsp; and&nbsp; 50 mg/ml while&nbsp; the <br />minimum bactericidal concentration ranged between 35 and 60 mg/ml. <em>A. jacquemontii</em> could be a potential <br />source of antimicrobial agents.&nbsp; <br />&nbsp;<br /><strong>Key words: </strong>Antibacterial; Antifungal; Baonli; Medicinal plants.&nbsp; <br /><br />DOI: 10.3329/sjps.v2i2.2384<br /><br /><em>Stamford Journal of Pharmaceutical Sciences</em> Vol.2(2) 2009: 21-26 ER -