Cerebral malaria in children : an update

Authors

  • Mirza Md Ziaul Islam Assistant Professor, Dept. of Pediatric Infectious Diseases & Community Pediatrics, Dhaka Shishu (Children) Hospital, Dhaka
  • M Mizanur Rahman Associate professor & Head, Dept. of Pediatric Infectious Diseases & Community Pediatrics, Dhaka Shishu (Children) Hospital, Dhaka

DOI:

https://doi.org/10.3329/nimcj.v6i2.23168

Keywords:

Cerebral malaria, encephalopathy, antimalarials

Abstract

Cerebral malaria (CM) is the most severe neurological presentation of acute falciparum malaria. It is a medical emergency, the hallmark of which is the presence of coma probably due to diffuse encephalopathy. A compromised microcirculation with sequestration of parasitized erythrocytes is central to the pathogenesis of cerebral malaria. The death is unacceptably high even with effective antimalarials in tertiary care hospital. The mainstay of treatment of cerebral malaria include prompt diagnosis and early institution of effective antimalarial therapy, recognition of complications, and appropriate supportive management in an ICU. Neurological sequlae are increasingly recognized, but further research on the pathogenesis of coma and neurological damage is required to develop other ancillary treatments

Northern International Medical College Journal Vol.6(2) 2015: 45-47

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Author Biography

Mirza Md Ziaul Islam, Assistant Professor, Dept. of Pediatric Infectious Diseases & Community Pediatrics, Dhaka Shishu (Children) Hospital, Dhaka



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Published

2015-05-01

How to Cite

Islam, M. M. Z., & Rahman, M. M. (2015). Cerebral malaria in children : an update. Northern International Medical College Journal, 6(2), 45–47. https://doi.org/10.3329/nimcj.v6i2.23168

Issue

Section

Review Articles