Mediscope Official journal of Gazi Medical College, Khulna, Bangladesh. Gazi Medical College Khulna en-US Mediscope 2307-7689 <p>Authors who publish in the Mediscope agree to the following terms that:</p><ol start="1"><li>Authors retain copyright and grant Mediscope the right of first publication of the work.<br /><br /></li><li><a href="" rel="license"><img style="border-width: 0;" src="" alt="Creative Commons Licence" /></a><br />Articles in Mediscope are licensed under a <a href="" rel="license">Creative Commons Attribution 4.0 International License</a> CC BY-4.0. This license permits use, distribution and reproduction in any medium, provided the original work is properly cited.</li></ol><ol start="3"><li>Authors are able to enter into separate, additional contractual arrangements for the distribution of the journal’s published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.</li><li>Authors are permitted to post their work online (e.g., in institutional repositories or on their website) as it can lead to productive exchanges, as well as greater citation of published work.</li></ol> Antibacterial effect of Dimethyl sulfoxide extract of Aloe vera (Aloe barbadensis) leaf gel against Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli and Klebsiella pneumoniae <p>An exploratory study based on laboratory experiment was carried out to determine the antibacterial effect of Dimethyl sulfoxide (DMSO) extract of Aloe vera leaf gel (DAE) against standard strains of Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli and Klebsiella pneumoniae in the Department of Pharmacology &amp; Therapeutics in collaboration with the Department of Microbiology, Mymensingh Medical College, Mymensingh, Bangladesh. DMSO extract was used in five different concentrations (100, 200, 300, 400 and 500 μg/ml). Dose dependent inhibitory effect was seen against the test organisms using disc diffusion method. Zone of inhibition (ZOI) were 8 mm, 13 mm, 15 mm, 16 mm and 21 mm against S. aureus; 0 mm, 8 mm, 13 mm, 15 mm and 18 mm against P. aeruginosa; 8 mm, 11 mm, 13 mm, 16 mm and 20 mm against E. coli; 0 mm, 9 mm, 12 mm, 14 mm and 18 mm against K. pneumoniae at 100, 200, 300, 400 and 500 μg/ml respectively. The minimum inhibitory concentration (MIC) was assessed by broth dilution technique. The MICs of DAE for S. aureus, P. aeruginosa, E. coli and K. pneumoniae were 300 μg/ml, 400 μg/ml, 400 μg/ml and 450 μg/ml respectively. From the study it was observed that DMSO extract of Aloe vera leaf gel possesses antibacterial effect against the test pathogens. The findings highlight the need for further extensive study to detect and isolate the biologically active ingredients present in the Aloe vera leaves which are responsible for antibacterial effect. Hopefully, that would lead to the discovery of new and more potent antimicrobial agents originated from Aloe vera.</p> <p>Mediscope Vol. 7, No. 2: July 2020, Page 67-74</p> Syed Didarul Haque Abu Md Mayeenuddin Al Amin Baishakhi Islam Nazia Nazneen Syeda Noorjahan Karim Md Abdur Rahman ##submission.copyrightStatement## 2020-09-29 2020-09-29 7 2 67 74 10.3329/mediscope.v7i2.49444 A study on health related risk factors and health seeking behavior among elderly population in rural Bangladesh <p>Globally, 10% of the world population is elderly people and it is expected to increase to 21% in the year 2051. In the year 2002, the number of elderly people in the world was estimated to be 605 million, which is expected to rise to more than 1.2 billion by the year 2025. This crosssectional study was conducted to and out the health-related quality of life and risk factors among elderly population in the selected rural population of Shyamnagar Upazila of Satkhira District. Data was collected from both the male and female population, aged 60 years and above, during February to June 2018. Purposive sampling technique was used to collect data from 50 respondents by face to face interview with semi-structured questionnaire. In the study, the mean age of elderly was male 63 (±2.95) years, and female 61.8 (±2.04) years. Other socio-demographic factors among elderly were as follows: 20 (40%) of elderly were illiterate, 15 (30%) of elderly were doing business, 21 (42%) were doing farming. 40 (80%) of elderly were married. The study also reported the five most common disease co-morbidities for elderly which included: 71.43% male and 28.57% female had hypertension while 72.22% of male and 27.78% of female patients were already treated, 68.75% male and 31.25% female had diabetes mellitus and 100% of them were treated, 50% of male elderly and 50% of female elderly were suffering bone and joint pain/arthritis and 60% of them were received treatment, hearing impairment found among 100% of male while two-third of patients received treatment, one-third of female and two-third of male elderly suffered from poor vision; however, only one-third of female patients were treated. On the basis of these findings, it can be recommended that there is a need to develop geriatric health-care services.</p> <p>Mediscope Vol. 7, No. 2: July 2020, Page 75-81</p> Farhana Ferdaus Refat Zahan Md Abdur Rahman Shahin Chowdhury ##submission.copyrightStatement## 2020-09-29 2020-09-29 7 2 75 81 10.3329/mediscope.v7i2.49445 Screening for cervical cancer in younger women may be an issue - A comparative study <p>Cervical cancer is a burning issue in our health sector. A project on cervical &amp; breast cancer screening has been running already in Bangladesh. All sexually active women of 30-years and above or those who are married for 10 years or more are included in this project. But significant numbers of women, less than 30 years of age were referred to Colposcopy clinic for evaluation. They also had high grade lesion. The purpose of this study was to identify the need for cervical cancer screening programme in younger women who are less than 30 years old. This is a comparative retrospective study conducted in 30 years old women and less than 30 years old (21-29 years) women, who were attending Colposcopy clinic for evaluation &amp; treatment in Khulna Medical College &amp; Hospital (KMCH) from January 2013 to December 2013. We analysed 235 Colposcopies in 225 women (30 years old in Group-A; less than 30 years old in Group-B) who were attending at Colposcopy clinic in Khulna Medical College Hospital in 2013. Among group A (n=90), colposcopic findings were: normal-36 (40%), CIN I-30 (33.33%), CIN II-15 (16.67%), CIN III-2 (2.22%), invasive carcinoma-3 (3.33%). Among group B (n=135), colposcopic findings were: normal-52 (38.52%), CIN I-38 (28.14%), CIN II-26 (19.25%), CIN III-3 (2.22%), invasive carcinoma-2 (1.48%). There characteristics were analysed and compared with each other. Although cervical cancer is extremely rare at younger age, there is increasing rate of younger women with high grade cervical lesion who may need treatment. It seems that these lesions have comparable behaviors as in older women. Early age of marriage is responsible for developing cervical cancer &amp; precancerous conditions. So screening should be started in earlier. Careful colposcopic assessment and evaluation before treatment remain indispensable in this regard.</p> <p>Mediscope Vol. 7, No. 2: July 2020, Page 82-88</p> Eti Saha Fouzia Begum Amina Jannat Peea Dipanwita Saha Dolly Halder ##submission.copyrightStatement## 2020-09-29 2020-09-29 7 2 82 88 10.3329/mediscope.v7i2.49446 A study on features and functions of family which are relevant to health behavior affecting family health of selected rural population in Bogura district <p>A descriptive type of Cross Sectional study was conducted in two villages named Joyvoga and Chokvochia of Gabtoli upazila, Bogra with a view to finding out the certain features and functions of family which are relevant to health behavior of selected rural population of Bogura district during the period of 20th and 23rd April 2015. Total 278 families were selected purposively. The respondents were aged 15 years and above and the data were collected through open ended pretested questionnaire by face to face interview. Out of 278 respondents, it was found that majority 121 (43.52%) of the respondents were within 31-45 years age group followed by 79 (28.41%) within the age group 15-30 years. Most of the respondents were females 165 (59.32%), agricultural workers 78 (28.05%), Muslims 276 (99.28%) &amp; one- third of the respondents completed their primary education 78 (28.06%). It was found that majority of the families are nuclear 193 (69.42%). Regarding housing condition, majority had satisfactory ventilation status (84.17%), safe water using (93.17%), using of sanitary latrine (87.05%), satisfactory cleanliness (38.12%) &amp; domestic waste disposal 25.18%. In case of child (under five) rearing majority were average in weight (88.85%) followed by underweight (7.91%), clean clothing condition (41.01%). Regarding socialization, attending social clubs 22.3%, schooling 78.42%, attending mosque 84.06% and taking part in games 87.77%. In case of personality formation most of the respondents can cope with the stress on an average 60.43% &amp; had good relation with children (73.55%). In relation to care of the dependent adults most 82.56% of the chronically sick persons did not get proper care, majority (85.77%) got satisfactory care during pregnancy. In relation to family condition most of the families are problem family (90.2%) followed by peaceful family (9.73%). Regarding stress related diseases, majority suffered from hypertension (25.30%) followed by Peptic Ulcer Disease (24.10%). This study will help to early detection of health related wrong behavior &amp; maintenance of family norm can prevent further breakdown of diseases related to family health of the rural people.</p> <p>Mediscope Vol. 7, No. 2: July 2020, Page 89-94</p> Md Jahangir Alam Khondoker Mohammad Ali Afsana Mahjabin Jarif Mahmud Tamjid Tajkeya Tamannum ##submission.copyrightStatement## 2020-09-29 2020-09-29 7 2 89 94 10.3329/mediscope.v7i2.49447 Comparison between fractionated dose with bolus dose in Spinal Anaesthesia for haemodynamic stability and duration of analgesia in patients undergoing elective Lower Segment Caesarean Section (LSCS) <p><strong>Background: </strong>Elective or emergency caesarean sections are routinely done under spinal anaesthesia (SA) with bolus dose of local anaesthetic drugs. Objective: To compared fractionated dose with bolus dose in SA for haemodynamic stability and duration of analgesia in patients undergoing elective lower segment caesarean section (LSCS).</p> <p><strong>Methods: </strong>The present study was carried out in the Department of Anaesthesiology, Ad-din Akij Medical College Hospital, Khulna from January 2018 to December 2018 on sixty female patients (thirty in each group) of the American Society of Anesthesiologists physical status I–III, age from 18 to 40 years, height from 140 to 180 cm, singleton pregnancies scheduled for elective LSCS under SA. Patients with pre-existing diseases or pregnancy-induced hypertension, cardiovascular or cerebrovascular disease, any contraindication to SA, those weighing &lt;50 kg or &gt;110 kg and those taller than 180 cm or shorter than 140 cm and severely altered mental status, spine deformities or history of laminectomy were excluded from the study.</p> <p><strong>Results: </strong>The mean duration of analgesia was statistically significant (p&lt;0.05) between two groups. Mean pulse rate- after 5 min, after 10 min, after 15 min, after 30 min, after 45 min and after 60 min were significantly (p&lt;0.05) higher in group F than group B. Mean arterial pressure- before given study drug, after 0 min, after 5 min, after 10 min, after 15 min, after 30 min, after 45 min and after 60 min were not significantly (p&gt;0.05) between two group. 14 patients (46.7%) in group B and 5 patients (16.7%) in group F required vasopressor. The difference was significant (p&lt;0.05) between two groups.</p> <p><strong>Conclusion: </strong>Separation process in which a certain quantity of a mixture dose of SA provides better haemodynamic stability and longer period of analgesia compare to bolus dose in patients undergoing elective caesarean section.</p> <p>Mediscope Vol. 7, No. 2: July 2020, Page 95-102</p> Md Munjur Hossain Biplab Biswas Pankaj Kumar Mohanta Muhammad Masud Hassan Plabon Basu Farhana Islam ##submission.copyrightStatement## 2020-09-29 2020-09-29 7 2 95 102 10.3329/mediscope.v7i2.49448 A cross-sectional study to determine the prevalence of obesity, overweight and weight awareness among the students of a private medical college in Khulna <p><strong>Background: </strong>Medical education is stressful throughout the whole course. Due to the medical curriculum and the examination pattern leads to psychological stress. Stressful condition leads to irregularity in diet, frequent fast food consumption &amp; lack of exercise, each being considered as an important risk factor leading to overweight and obesity. Hence, this study was undertaken to determine the prevalence of obesity, overweight and weight awareness among the medical students.</p> <p><strong>Objectives: </strong>Determination of BMI status of undergraduate medical students to evaluate their weight awareness, prevalence of overweight and obesity and also find out the relationship of the following risk factors with obesity &amp; overweight; i) Opinion about self-image, ii) Physical activity and iii) Frequency of fast food consumption.</p> <p><strong>Methods: </strong>A descriptive cross sectional study was conducted on 131 preclinical medical students of Ad-din Akij Medical College, Khulna from January 2018 to April 2018. Height and weight of 131 preclinical students were measured and Body Mass Index was calculated and categorized according to WHO criteria.</p> <p><strong>Results: </strong>Out of 131 students 62% come under normal weight category, 21% come under overweight category, 10% come under obese category and 7% come under underweight category.</p> <p><strong>Conclusion: </strong>Overweight is a rising problem among the medical students. Sedentary life style and frequency of fast food consumption was high among the overweight and obese students. This study itself created awareness about their weight and promote physical activity among the medical students.</p> <p>Mediscope Vol. 7, No. 2: July 2020, Page 103-107</p> Md Abul Hasanat Silvia Paroi Arifa Begum Umme Salma Syeda Farzana Yeasmin ##submission.copyrightStatement## 2020-09-29 2020-09-29 7 2 103 107 10.3329/mediscope.v7i2.49449 Fetal outcome in Premature Rupture of Membrane – A study conducted in a tertiary level hospital in Bangladesh <p><strong>Background: </strong>Perinatal mortality is high if premature rupture of membrane (PROM) occurs when fetuses are of previable gestational age.</p> <p><strong>Objective: </strong>To find out the effect of premature rupture of membrane in pregnancy on its fetal outcome.</p> <p><strong>Methods: </strong>A cross-sectional study was conducted in Department of Obstetrics and Gynaecology of Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh, from February to July of 2008, on 50 pregnant women with more than 28 weeks of pregnancy both primigravid and multigravid with rupture of membranes prior to labour. Women who were admitted with rupture of membranes with established labour, or having antepartum hemorrhage, pre-eclampsia or eclampsia were excluded from the study. Out of 775, only 95 patients were admitted with history of premature rupture of membrane (PROM). Among those patients, 50 cases were included in this study as per inclusion and exclusion criteria. Then their mode of delivery and outcome of fetal parameters were recorded.</p> <p><strong>Results: </strong>48 live births were observed and there were 2 fetal losses. Among 48 live newborns, 28 (58.33%) were male and 20 (41.66%) were female. 54.16% of babies had APGAR score at 5 minutes after birth was &gt;7 and those needed no treatment. APGAR score was 7 in 45.82% babies; all of them were treated and cured. Among the newborns, 52.08% babies had birth weight &gt;2500 gm, 45.83% had their birth weight in between 1500 and 2500 gm, while 1 (2.08%) was between 1000 and 1500 gm. However, 22 (45.83%) were affected by the consequences of PROM and birth process. Among them, 36.36% developed jaundice, 29.27% suffered from birth asphyxia, and RTI and neonatal sepsis were evident in 18.18% each. 15% babies were treated conservatively in Department of Obstetrics, while 7% babies were treated in the Neonatal Ward under Department of Paediatrics after admission.There was no neonatal loss.</p> <p><strong>Conclusion: </strong>Despite progress in obstetric and neonatal care over the past few years, fetal outcomes in pregnancies with PROM remains disappointing to date.</p> <p>Mediscope Vol. 7, No. 2: July 2020, Page 108-112</p> Sanchita Adhikary Shaorin Tanira Arifa Sultana Feroza Wazed Saleha Begum Chowdhury ##submission.copyrightStatement## 2020-09-29 2020-09-29 7 2 108 112 10.3329/mediscope.v7i2.49450 Practice of contraceptive methods among the outdoor patients in a tertiary level hospital <p>The study to determine the practice contraceptive method among married women attended in the out-door patients in Ad-din Sakina Women’s Medical College Hospital from 2nd November to 12th November in 2015. Nine hundred thirty five married women were interview on practice of contraceptive methods. Result shows highest number of choice among the respondents was oral pill, followed by condom, injection, IUCD. Through, contraceptive methods acceptance rate is increased still unmet need for contraceptive method was present. The country should come forward to face the challenges to safe country from disaster of over population.</p> <p>Mediscope Vol. 7, No. 2: July 2020, Page 113-116</p> Serajul Islam Sanjoy Saha Khan Shakil Ahmed Mir Moyeedul Islam Susmita Nargis Kishore Kumar Bishwas ##submission.copyrightStatement## 2020-09-29 2020-09-29 7 2 113 116 10.3329/mediscope.v7i2.49451 Gastro Coronavirus: A new era <p>Coronavirus is a highly infectious contagious virus producing pandemic throughout the world with high morbidity and mortality. Right now, there is no vaccine to prevent human coronavirus infections. But you mayable to reduce your risk of getting or spreading an infection by-washing hands often with soap and water for at least 20 seconds,using an alcohol-based hand sanitizer that contains at least 70% alcohol if soap and water are not available, avoiding touching your face, nose, or mouth with unwashed hands,use of face mask, avoiding close contact with people who are sick.There is no specific treatment for coronavirus. Treatment aims to relieve the symptoms. Most people will get better on their own. However, you can relieve your symptoms by-taking over-the-counter medicines for pain, fever, and cough&amp;plenty of nutritious diet, drinking fluids and taking rest.</p> <p>Mediscope Vol. 7, No. 2: July 2020, Page 117-125</p> Md Abdul Ahad ##submission.copyrightStatement## 2020-09-29 2020-09-29 7 2 117 125 10.3329/mediscope.v7i2.49452