Effects of concentration and synergism on drug solubilising behaviour of PVP K 30 and PEG 6000

  • Jannatul Fardous Department of Pharmacy, Jahangirnagar University, Savar, Dhaka-1342
  • Faria Farzana Perveen Department of Pharmacy, Jahangirnagar University, Savar, Dhaka-1342
  • Md Ohidullah Department of Pharmacy, Jahangirnagar University, Savar, Dhaka-1342
  • AHM Saifuddin Department of Pharmacy, Jahangirnagar University, Savar, Dhaka-1342
  • Sakina Sultana Department of Pharmacy, Jahangirnagar University, Savar, Dhaka-1342
Keywords: PVP K 30, PEG 6000, PEG 20000, Tween 80 and Theophylline

Abstract

The effect of concentration and synergism on drug solubilising behaviour of PVP K 30 and PEG 6000 were investigated. Our results showed that amount of drug solubilised by the surfactants decreased as surfactant concentration was increased. Regarding the effect of synergism of the two surfactants on drug solubilisation our results failed to show synergism. The amount of drug solubilised by a single surfactant did not differ much when combination of surfactants were used.

Jahangirnagar University J. Biol. Sci. 3(2): 49-55, 2014 (December)

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Author Biography

Jannatul Fardous, Department of Pharmacy, Jahangirnagar University, Savar, Dhaka-1342


Published
2016-06-19
How to Cite
Fardous, J., Perveen, F., Ohidullah, M., Saifuddin, A., & Sultana, S. (2016). Effects of concentration and synergism on drug solubilising behaviour of PVP K 30 and PEG 6000. Jahangirnagar University Journal of Biological Sciences, 3(2), 49-55. https://doi.org/10.3329/jujbs.v3i2.28285
Section
Original Research Articles