Analgesic, anti-inflammatory, anticonvulsant and CNS effect of the ethanolic extract of Butea monosperma roots
The analgesic, anti-inflammatory, anticonvulsant and CNS activities of the ethanolic extract of Butea monosperma roots were examined. The extract produced no significant inhibition of abdominal constrictions caused by acetic acid. It showed significant inhibition of the earlyphase of formalin-induced pain, also reduced the weight of granuloma induced by a cotton pellet. Moreover, the extract caused a moderate inhibition of ear swelling in mice caused by croton oil. In pentobarbital induced sleeping time test the extract slightly reduced the onset and increased the duration of sleeping. Therefore, Butea monosperma showed analgesic, antiinflammatory, mild anticonvulsant activities as well as sedative effect on CNS.
Jahangirnagar University J. Biol. Sci. 4(1): 9-18, 2015 (June)
Copyright (c) 2016 Jahangirnagar University Journal of Biological Sciences
This work is licensed under a Creative Commons Attribution 4.0 International License.
(c) Jahangirnagar University Journal of Biological Sciences.
Articles in the Jahangirnagar University Journal of Biological Sciences are Open Access articles published under the Creative Commons CC BY License (https://creativecommons.org/licenses/by/4.0/). This license permits use, distribution and reproduction in any medium, provided the original work is properly cited.