Imipenem Resistance Gram-Negative Bacilli Isolated from Patients of a Tertiary Care Hospital in Dhaka, Bangladesh

Authors

  • Hasbi Ara Mostofa Assistant professor, Department of Microbiology, Shaheed Suhrawardy Medical College, Dhaka
  • SM Shamsuzzaman Professor and Head, Department of Microbiology, Dhaka Medical College, Dhaka
  • Md Maniul Hasan Assistant professor, Department of Surgery, Shaheed Suhrawardy Medical College, Dhaka
  • Moonmoon Shormin Assistant professor, Department of Microbiology, Shaheed Monsur Ali Medical College, Dhaka
  • Bithi Das Assistant professor, Department of Microbiology, Shaheed Suhrawardy Medical College, Dhaka
  • Umme Habiba Assistant professor, Department of Microbiology, Shaheed Suhrawardy Medical College, Dhaka
  • Md Mustafizur Rahman Professor and Head, Department of Surgery, Shaheed Suhrawardy Medical College, Dhaka
  • Shakila Akhter Assistant Professor, Department of Pharmacology, National Institute of Cardiovascular Disease (NICVD), Dhaka

DOI:

https://doi.org/10.3329/jssmc.v12i1.51610

Keywords:

Antibiotic resistance, Imipenem, Gram-negative bacilli.

Abstract

Introduction: The emergence of antibiotics resistance bacteria is a persistent global problem affecting public health. The occurrence and widespread resistance to Imipenem among hospital bacterial isolates can constitute a significant threat to chemotherapy.

Objectives: This cross-sectional study aimed to investigate the imipenem resistant pattern among gram-negative bacilli isolated from different samples in Dhaka medical college hospital.

Methods: A total of 300 samples (wound swab, urine, endotracheal aspirate, blood, and sputum) were collected from July 2015 to June 2016. Two hundred four gram-negative bacilli were isolated and tested for resistance to imipenem by the disc diffusion method.

Results: Among 204-gram negative bacilli, 39.21% imipenem resistance was detected by the Disc Diffusion method. 14.7% imipenem resistance gram-negative bacilli were from wound swab. 83.33% of Acinetobacter baumannii were Imipenem resistant.

Conclusions: Imipenem resistance is widespread among gram-negative bacilli isolated from human infections. Imipenem resistance (39.21%) found in the study is quite worrisome.

J Shaheed Suhrawardy Med Coll, December 2020, Vol.12(1); 3-5

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Published

2021-01-24

How to Cite

Mostofa, H. A., Shamsuzzaman, S., Hasan, M. M., Shormin, M., Das, B., Habiba, U., Rahman, M. M., & Akhter, S. (2021). Imipenem Resistance Gram-Negative Bacilli Isolated from Patients of a Tertiary Care Hospital in Dhaka, Bangladesh. Journal of Shaheed Suhrawardy Medical College, 12(1), 3–5. https://doi.org/10.3329/jssmc.v12i1.51610

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