Thin Layer Chromatography-A Tool to Investigate Kinetics of Michael Addition Reaction

Authors

  • M. A. B. H. Susan Department of Chemistry Dhaka University Dhaka 1000, Bangladesh http://orcid.org/0000-0003-0752-1979
  • G. Ara Department of Chemistry University of Dhaka Dhaka 1000, Bangladesh and Department of Chemistry Jagannath University, Dhaka, Bangladesh
  • M. M. Islam Department of Chemistry University of Dhaka Dhaka 1000, Bangladesh
  • M. M. Rahman Department of Chemistry University of Dhaka Dhaka 1000, Bangladesh
  • M. Y. A. Mollah University Grants Commission of Bangladesh 29/1 Agargaon, Sher-E-Banglanagar, Dhaka, Bangladesh

DOI:

https://doi.org/10.3329/jsr.v10i3.37190

Keywords:

Thin layer chromatography, Michael addition reaction, Catalyst, Average rate.

Abstract

Thin layer chromatography (TLC), a tool for defining identity, purity, and quantitation of a compound, has also been proved useful for monitoring the progress of a chemical reaction. However, the   technique is yet to be exploited for investigating the kinetics of a reaction systematically. In this work, we used TLC for measuring the time for consumption of a reactant in Michael addition reaction of acetylacetone with 2-cyclohexene-1-one. Average rate of the model reaction was determined using a definite initial concentration of acetylacetone for a series of catalyst systems like NaOH, 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU), DBU based protic ionic liquids (PILs) 1,8-diazabicyclo[5.4.0]undec-7-ene-8-ium hydroxide ([HDBU]OH) and 1,8-diazabicyclo[5.4.0]undec-7-ene-8-ium acetate ([HDBU]CH3COO), a DBU based aprotic ionic liquid (AIL), 8-hexyl-1,8-diazabicyclo [5.4.0]undec-7-ene-8-ium hydroxide ([C6DBU]OH), and binary systems of the ionic liquids with molecular solvents, such as, water, DBU, and acetic acid. The kinetic data on the performance of the chosen catalysts were interpreted on the basis of the established mechanism of the reaction. Finally, the prospect of the method based on TLC as a suitable technique for kinetic study of chemical reactions has been discussed.

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Author Biographies

M. A. B. H. Susan, Department of Chemistry Dhaka University Dhaka 1000, Bangladesh

Professor of Chemistry

G. Ara, Department of Chemistry University of Dhaka Dhaka 1000, Bangladesh and Department of Chemistry Jagannath University, Dhaka, Bangladesh

Assistant Professor of Chemistry

M. M. Islam, Department of Chemistry University of Dhaka Dhaka 1000, Bangladesh

Associate Professor of Chemistry

M. Y. A. Mollah, University Grants Commission of Bangladesh 29/1 Agargaon, Sher-E-Banglanagar, Dhaka, Bangladesh

Professor of Chemistry and Member, UGC

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Published

2018-09-01

How to Cite

Susan, M. A. B. H., Ara, G., Islam, M. M., Rahman, M. M., & Mollah, M. Y. A. (2018). Thin Layer Chromatography-A Tool to Investigate Kinetics of Michael Addition Reaction. Journal of Scientific Research, 10(3), 323–329. https://doi.org/10.3329/jsr.v10i3.37190

Issue

Section

Section B: Chemical and Biological Sciences