Spectral and Biological Studies on New Mixed Ligand Complexes

Authors

  • T. K. Pal Rajshahi University of Engineering & Technology (RUET)
  • M. A. Alam Rajshahi University of Engineering & Technology (RUET)
  • J. Hossen Rajshahi University of Engineering & Technology (RUET)
  • S. Paul University of Rajshahi
  • H. Ahmad University of Rajshahi
  • M. C. Sheikh University of Toyama

DOI:

https://doi.org/10.3329/jsr.v10i3.36379

Keywords:

Bis(2, 4, 4-trimethylpentyl)dithiophosphinic acid, SEM, Antioxidant.

Abstract

In this study, new mixed ligand complexes have been prepared from bis(2,4,4-trimethylpentyl)dithiophosphinic acid (C16H35PS2) and 2,9-dimethyl-1,10-phenanthroline (C14H12N2) with various metal(II) ions. The molecular formula of the metal complexes were [Mn(C16H34PS2)(C14H12N2)]Cl (1), [Fe(C16H34PS2)(C14H12N2)]Cl (2), [Co(C16H34PS2) (C14H12N2)]Cl (3), [Zn(C16H34PS2)(C14H12N2)]Cl (4) and [Cd(C16H34PS2)(C14H12N2)]Cl (5). These complexes have been characterized by various physico-chemical techniques such as melting point, molar conductance, magnetic susceptibility measurements as well as UV-Vis, IR, TG and mass spectroscopic analyses. The surface morphology was determined by scanning electron microscope (SEM). The magnetic moment value, color as well as spectral measurements suggested that the geometrical structures of the metal complexes were tetrahedral. The spectral data showed that bis(2,4,4-trimethylpentyl)dithiophosphinic acid and 2,9-dimethyl-1,10-phenanthroline ligands  acted as uninegative and neutral bidentate ligand, respectively. The obtained mixed ligand complexes were more stable in air and highly soluble in common organic solvent. The bio-efficacy of ligands and metal complexes have been screened against the test microorganism using agar disc diffusion method. The complex 4 showed potential antibacterial activity against Sterptococcus aureus as compared to standard drug, imipenem. On the other hand, the complex 3 also displayed more potent antifungal activity against Lecanicillium fungicola. Moreover, the complex 3 was also found to have better scavenging activity against 2,2-diphenyl-1-picrylhydrazyl.

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Author Biographies

T. K. Pal, Rajshahi University of Engineering & Technology (RUET)

Department of Chemistry and Assistant Professor

M. A. Alam, Rajshahi University of Engineering & Technology (RUET)

Department of Chemistry and Professor

J. Hossen, Rajshahi University of Engineering & Technology (RUET)

Department of Chemistry and Lecturer

 

S. Paul, University of Rajshahi

Department of Pharmacy and M. Pharm Student

H. Ahmad, University of Rajshahi

Department of Chemistry and Professor

M. C. Sheikh, University of Toyama

Department of Applied Chemistry and Postdoctoral researcher 

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Published

2018-09-01

How to Cite

Pal, T. K., Alam, M. A., Hossen, J., Paul, S., Ahmad, H., & Sheikh, M. C. (2018). Spectral and Biological Studies on New Mixed Ligand Complexes. Journal of Scientific Research, 10(3), 291–302. https://doi.org/10.3329/jsr.v10i3.36379

Issue

Section

Section B: Chemical and Biological Sciences