Radioiodine Thyroid Uptake and Scintigraphy in the Evaluation of Hyperthyroidism with Multinodular Goiter

Authors

  • M. R. Islam Department of Physics, University of Rajshahi, Rajshahi-6205.
  • F. N. Islam Department of Physics, University of Rajshahi, Rajshahi-6205.
  • M. M. Haque Department of Physics, University of Rajshahi, Rajshahi-6205.
  • M. S. Hossain Institute of Nuclear Medicine and Allied Sciences (INMAS), Bangladesh Atomic Energy Commission, Dhaka.
  • M. S. Reza Institute of Nuclear Medicine and Allied Sciences (INMAS), Bangladesh Atomic Energy Commission, Dhaka.
  • R. Begum Institute of Nuclear Medicine and Allied Sciences (INMAS), Bangladesh Atomic Energy Commission, Dhaka.

DOI:

https://doi.org/10.3329/jsr.v10i3.33225

Keywords:

Thyroid uptake, Scintigraphy, Multinodular goiter, Radioactive iodine, 99mTc-pertechnetate.

Abstract

The role of radioactive iodine uptake and scintigraphy were studied over 111 subjects with a mean age of 42±13 years, 65% females and 35% males, in the evaluation of hyperthyroidism with multinodular goiter. The uptake study was performed by oral administration of 4.5 – 10.0 μCi of 131I as sodium-iodide thyroid scintigraphy was performed 20 minutes after an intravenous injection of 2.0 – 4.0 mCi of 99mTc as pertechnetate. The Mean ± SD uptake values for the study subjects were found to be 36.1±15.4% ranging from 14% to 75% at 2 h and 59.9±15.9% ranging from 32% to 90% at 24 h measurements. The present results of uptake values clearly exceed the normal range (3% – 12% for 2 h; 8% – 25% for 24 h), which indicate the hyper-functioning of thyroid, and therefore, demonstrated successfully the efficient role of radioactive iodine uptake and scintigraphy to diagnose the hyperthyroidism.

 

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Published

2018-09-01

How to Cite

Islam, M. R., Islam, F. N., Haque, M. M., Hossain, M. S., Reza, M. S., & Begum, R. (2018). Radioiodine Thyroid Uptake and Scintigraphy in the Evaluation of Hyperthyroidism with Multinodular Goiter. Journal of Scientific Research, 10(3), 223–229. https://doi.org/10.3329/jsr.v10i3.33225

Issue

Section

Section A: Physical and Mathematical Sciences