Evaluation of Free Radical Scavenging and Polyphenolic Contents of Bark of <i>Pterygota alata</i> Roxb

Authors

  • N. Jahan Reneta Pharma Ltd.
  • M. S. Parvin Rajshahi University
  • A. Khan Rajshahi University
  • N. Das Reneta Pharma Ltd.
  • M. S. Islam Rajshahi University
  • M. E. Islam Rajshahi University

DOI:

https://doi.org/10.3329/jsr.v6i3.17586

Keywords:

Free radical, Reactive oxygen species, DPPH, Ferric reducing power, Polyphenols.

Abstract

Pterygota alata is a large deciduous tree of Malvaceae family. The present study was designed to evaluate in vitro antioxidant activity of stem bark of the plant. Ferric reducing power (FRP) test, 1, 1- diphenyl-2-picryl hydrazyl (DPPH) free radical scavenging test and total antioxidant capacity (TAC) assay were used to detect the antioxidant activity. Total phenolic and flavonoid contents were also determined as they are well known phytochemicals with antioxidant property. The bark of the plant showed efficient reducing power as well as free radical scavenging property (IC50 values 52.25 - 172.05). The bark also found rich in total phenolic and flavonoid content. The highest amount of total phenolic content was found in chloroform soluble fraction (29.898 µg/mL) followed by ethyl acetate soluble fraction (15.88 µg/mL). The highest content of total flavonoid also detected in chloroform soluble fraction (107.56 µg/mL) but followed by crude ethanol extract (98.66 µg/mL). Overall, the bark of the plant possesses significant antioxidant activity, therefore can be used as a good natural source of antioxidant.

© 2014 JSR Publications. ISSN: 2070-0237 (Print); 2070-0245 (Online). All rights reserved.

doi: http://dx.doi.org/10.3329/jsr.v6i3.17586 J. Sci. Res. 6 (3), 543-552 (2014)

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Author Biographies

N. Jahan, Reneta Pharma Ltd.

QC section

Executive

M. S. Parvin, Rajshahi University

Dept. of Pharmacy, Associate Professor

A. Khan, Rajshahi University

Dept. of Pharmacy, Associate Professor

N. Das, Reneta Pharma Ltd.

QC section, Executive

M. S. Islam, Rajshahi University

Dept. of Pharmacy, Lecturer

M. E. Islam, Rajshahi University

Dept. of Pharmacy, Associate Professor

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Published

2014-08-26

How to Cite

Jahan, N., Parvin, M. S., Khan, A., Das, N., Islam, M. S., & Islam, M. E. (2014). Evaluation of Free Radical Scavenging and Polyphenolic Contents of Bark of <i>Pterygota alata</i> Roxb. Journal of Scientific Research, 6(3), 543–552. https://doi.org/10.3329/jsr.v6i3.17586

Issue

Section

Section B: Chemical and Biological Sciences