Antioxidant, Antimicrobial and Cytotoxic Activities of <i>Desmodium Motorium</i> Merr.

Authors

  • M. A. Alam Rajshahi University of Engineering & Technology (RUET)
  • T. K. Pal Rajshahi University of Engineering & Technology (RUET)
  • M. A. Chowdhury Rajshahi University of Engineering & Technology (RUET)
  • M. A. Rashid University of Dhaka
  • M. S. Rahaman University of Dhaka

DOI:

https://doi.org/10.3329/jsr.v5i1.10955

Keywords:

Desmodium motorium, Leguminosae, Antioxidant activity, Brine shrimp lethality.

Abstract

The n-hexane, carbon tetrachloride, dichloromethane soluble fractions of methanol extract of the whole plant of Desmodium motorium were subjected to antioxidant activity by indicated method, inhibition of microbial growth by disc diffusion method and cytotoxicity by brine shrimp lethality bioassay. The methanol i.e., crude extract showed highest antioxidant activity having IC50 9.5 ?g/ml as compared to 9.0 ?g/ml for standard agent BHT. The n-hexane, carbon tetrachloride and dichloromethane soluble fraction showed moderate inhibitory activity to microbial growth, while all the extractive exhibited strong cytotoxic property with the carbon tetrachloride soluble materials revealed the strongest cytotoxicity with LC50 1.54 ?g/ml.

© 2013 JSR Publications. ISSN: 2070-0237 (Print); 2070-0245 (Online). All rights reserved.

doi: http://dx.doi.org/10.3329/jsr.v5i1.10955         J. Sci. Res. 5 (1), 201-205 (2013)

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Author Biographies

M. A. Alam, Rajshahi University of Engineering & Technology (RUET)

Dept. of Chemistry

Professor

T. K. Pal, Rajshahi University of Engineering & Technology (RUET)

Dept. of Chemistry

 Lecturer

  

 

M. A. Chowdhury, Rajshahi University of Engineering & Technology (RUET)

Dept. of Chemistry

Ph. D Student

 

M. A. Rashid, University of Dhaka

Department of Pharmaceutical Chemistry

Professor

M. S. Rahaman, University of Dhaka

 

Department of Pharmaceutical Chemistry

Assistant Professor

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Published

2012-12-29

How to Cite

Alam, M. A., Pal, T. K., Chowdhury, M. A., Rashid, M. A., & Rahaman, M. S. (2012). Antioxidant, Antimicrobial and Cytotoxic Activities of <i>Desmodium Motorium</i> Merr. Journal of Scientific Research, 5(1), 201–205. https://doi.org/10.3329/jsr.v5i1.10955

Issue

Section

Section B: Chemical and Biological Sciences