@article{Hossain_Mohal_Islam_Yusuf_2013, title={Prevalence of Ciprofloxacin Resistance among Gram-Negative Bacilli Isolated From Urinary Tract Infection Specimens at a Specialist Hospital in Riyadh, Saudi Arabia}, volume={11}, url={https://www.banglajol.info/index.php/JSF/article/view/19395}, DOI={10.3329/jsf.v11i1.19395}, abstractNote={<p><strong>Background: </strong>Susceptibility to fluoroquinolones is very important information before prescribing to the urinary tract infection (UTI) patients. <strong>Objective:</strong> The purpose of the present study was to see the sensitivity pattern of the Gram-Negative bacilli isolated from urinary tract infection to various antibiotics as well as to know the prevalence rate of Ciprofloxacin resistance. <strong></strong></p><p><strong>Methodology: </strong>This cross sectional study was conducted in a specialized hospital in Riyadh, Saudi Arabia from January’2006 to June’2006 for over a period of six months. The Gram-negative bacilli (GNB) were isolated from clinical specimens of UTIs and antibiotic susceptibility testing was performed. Isolates with resistance or with a decreased susceptibility to Ciprofloxacin (20 mm) were than screened for their minimum inhibitory concentration (MIC) by using the E-test. <strong></strong></p><p><strong>Results:</strong> Out of 510 GNB, 97(19%) isolates were resistant to Ciprofloxacin. The MIC of these isolates ranged from 4 to 32µg/ml. Most of the Ciprofloxacin resistant isolates were from urinary tract infections (UTI) of hospital patients both (indoor & outdoor). The Ciprofloxacin resistance was also closely associated with multi-drug resistance, thus limiting the treatment options. <strong></strong></p><p><strong>Conclusion:</strong><em> </em>The considerably high MIC values for Ciprofloxacin in this study reflected the extent of the treatment problems for these resistant isolates.</p><p>DOI: <a href="http://dx.doi.org/10.3329/jsf.v11i1.19395">http://dx.doi.org/10.3329/jsf.v11i1.19395</a></p>}, number={1}, journal={Journal of Science Foundation}, author={Hossain, Md. Afzal and Mohal, Shirin and Islam, Md. Saiful and Yusuf, Mohammad Abdullah}, year={2013}, month={Jan.}, pages={11–16} }