TY - JOUR AU - Islam, Fahrima AU - Hossain, Amir AU - Hossain, Md Golam AU - Murshid, Gazi Md Monjur AU - Rahman, Md Mustafizur PY - 2015/06/18 Y2 - 2024/03/29 TI - Evaluation of Antioxidant, Analgesic and Cytotoxic Activities of Typha angustata L. Root JF - Dhaka University Journal of Pharmaceutical Sciences JA - Dhaka Univ. J. Pharm. Sci VL - 14 IS - 1 SE - Articles DO - 10.3329/dujps.v14i1.23736 UR - https://www.banglajol.info/index.php/JPharma/article/view/23736 SP - 55-59 AB - <p>Ethanolic extract of the root of Typha angustata was evaluated for antioxidant, analgesic and cytotoxic activities. T. angustata extract exhibited DPPH free radical scavenging activity with IC<sub>50</sub> value of 124.96 ± 0.93 ?g/ml. The total phenolic and tannin content were found to be 596.73 ± 1 mg GAE/100 g and 319.68 ± 64 mg GAE/100 g of dried plant material, respectively. Analgesic activity was determined using acetic acid induced writhing inhibition in mice model. The root extract, at doses of 250 mg/kg and 500 mg/kg body weight, showed inhibition of writhing reflex by 33.55% (p &lt; 0.01) and 56.78% (p&lt;0.001), respectively. Cytotoxicity of the extract was measured by brine shrimp lethality bioassay where the LC50 against brine shrimp nauplii was found to be 41.54?g/ml.</p><p>Dhaka Univ. J. Pharm. Sci. 14(1): 55-59, 2015 (June)</p> ER -