TY - JOUR AU - Islam, Md Torequl AU - Ibrahim, Mohammed AU - Ahsan, Md Qamrul AU - Chowdhury, M Mohi Uddin AU - Hossain, Md Aslam AU - Rashid, Mohammad A PY - 2012/11/04 Y2 - 2024/03/29 TI - Phytochemical and Pharmacological Investigations of Uraria lagopodies DC. and Urena lobata L. JF - Dhaka University Journal of Pharmaceutical Sciences JA - Dhaka Univ. J. Pharm. Sci VL - 11 IS - 1 SE - Articles DO - 10.3329/dujps.v11i1.12490 UR - https://www.banglajol.info/index.php/JPharma/article/view/12490 SP - 65-69 AB - <p>Easy availability and reduced side effects of plants and plant-derived herbal preparations are the gifts of nature and are useful since ancient time for the treatment of various diseases. From this view point twoBangladeshi plants, <em>Uraria lagopodies </em>DC. and <em>Urena lobata </em>L. have been evaluated for their possible pharmacological activities. Preliminary phytochemical screenings with the crude ethanol extracts demonstrated the  presence of alkaloids, glycosides, tannins, saponins, steroids and reducing sugars. The crude extract of <em>U. lagopodies </em>significantly (p&lt;0.001) increased the charcoal evacuation by 375 min at 500 mg/kg body weight of mice when  compared to the standard, Loperamide by 391.8 min at 5 mg/kg b.w. In the acetic acid induced analgesic activity test,  the oral administration of ethanol extract of <em>U. lobata </em>produced significant (p&lt;0.05) pain relieving activity (number  of writhing 32) at 500 mg/kg body weight as compared to standard diclofenac-Na. Both the crude extracts showed mild anti-inflammatory and membrane stabilizing activities during the heat induced anti-inflammatory test and  membrane stabilization screening. A dose dependent biological activity was observed during the study period.</p> <p>DOI: <a href="http://dx.doi.org/10.3329/dujps.v11i1.12490">http://dx.doi.org/10.3329/dujps.v11i1.12490</a></p> <p>Dhaka Univ. J. Pharm. Sci. <strong>11</strong>(1): 65-69, 2012 (June)</p> ER -