@article{Khair_Ibrahim_Ahsan_Kuddus_Rashid_Rashid_2015, title={Preliminary phytochemical screenings and Pharmacological activities of Blumea lacera (Burn.f.) DC.}, volume={13}, url={https://www.banglajol.info/index.php/JPharma/article/view/21863}, DOI={10.3329/dujps.v13i1.21863}, abstractNote={<p>The methanol extract of the whole plant of <em>Blumea lacera </em>(Burn.f.) DC. (BLME) has been subjected to preliminary screenings for phytoconstituents and antipyretic, analgesic and anti-inflammatory activities. Antipyretic activity was assessed by the yeast-induced hyperthermia in mice. The analgesic property was evaluated by formalin-induced writhing test. Acetyl salicylic acid (ASA) was used as standard for <em>in-vitro </em>anti-inflammatory activity test. In yeast-induced pyrexia, the crude extract demonstrated a significant (p=0.05) reduction in body temperature of mice after elevation by the administration of yeast. These effects were pronounced at the 2nd and 3rd h of post-treatment with the extract. BLME exhibited a dose-dependent analgesic activity with 39.13% and 56.52% protection at 200-and 400-mg/kg, b.w., respectively as compared to 76.09% revealed by the standard diclofenac sodium. In the anti-inflammatory test, the crude extract at 400 ?g/ml displayed 62.40% inhibition of protein denaturation whereas standard acetyl salicylic acid exhibited 76.74% inhibition. Results of the preliminary phytochemical screenings demonstrated the presence of alkaloids, flavonoids and triterpenoids in the extract.</p> <p>DOI: <a href="http://dx.doi.org/10.3329/dujps.v13i1.21863">http://dx.doi.org/10.3329/dujps.v13i1.21863</a></p> <p>Dhaka Univ. J. Pharm. Sci. 13(1): 69-73, 2014 (June)</p>}, number={1}, journal={Dhaka University Journal of Pharmaceutical Sciences}, author={Khair, Md Abul and Ibrahim, Mohammed and Ahsan, Qamrul and Kuddus, Md Ruhul and Rashid, Ridwan Bin and Rashid, Mohammad Abdur}, year={2015}, month={Feb.}, pages={69–73} }