Preliminary Anti-bacterial Activity of Some Indigenous Plants of Bangladesh

  • Hasina Yasmin Department of Pharmacy, State University of Bangladesh, Dhaka
  • Md Abu Kaiser Department of Pharmaceutical Chemistry, University of Dhaka, Dhaka
  • Md Moklesur Rahman Sarker Department of Immunochemistry, Division of Pharmaceutical Sciences, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Tsushima-naka, Okayama
  • Mohammed Shafikur Rahman Department of Production and Product Development, NOVO Healthcare and Pharma Ltd., Mirpur, Dhaka
  • Mohammad A Rashid Department of Pharmaceutical Chemistry, University of Dhaka, Dhaka
Keywords: Antibacterial activity, Disc diffusion method, Extract, Indigenous plants of Bangladesh

Abstract

The antibacterial activity of petroleum ether, carbon tetrachloride and chloroform soluble
fractions of crude methanol extracts of nine indigenous plant species of Bangladesh was evaluated by the agar
diffusion method. Kanamycin (30 μg/disc) was used as a standard antibacterial agent. The results indicated that
all the nine plant species (not all partitionates) exhibited moderate to potent antibacterial activity against a wide
variety of gram- positive and gram-negative bacteria at a concentration of 400μg/disc. Among them the carbon
tetrachloride soluble fraction of whole plant extract of Corriandrum sativum (family-Apiaceae) revealed the
highest antibacterial activity against Shigella boydii with zone of inhibition of 29 mm.

Key words: Antibacterial activity; Disc diffusion method; Extract; Indigenous plants of Bangladesh.

DOI: 10.3329/dujps.v8i1.5337

Dhaka Univ. J. Pharm. Sci. 8(1): 61-65, 2009 (June)

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Yasmin, H., Kaiser, M., Sarker, M., Rahman, M., & Rashid, M. (1). Preliminary Anti-bacterial Activity of Some Indigenous Plants of Bangladesh. Dhaka University Journal of Pharmaceutical Sciences, 8(1), 61-65. https://doi.org/10.3329/dujps.v8i1.5337
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