Phytochemical and Biological investigations of <i>Phoenix paludosa</i> Roxb.

Authors

  • Farzana Alam Department of Pharmacy, The University of Asia Pacific, Dhaka
  • Mohammad S Rahman Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka
  • Md Shahanur Alam Department of Pharmacy, The University of Asia Pacific, Dhaka
  • Md Khalid Hossain Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka
  • Md Aslam Hossain Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka
  • Mohammad A Rashid Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka

DOI:

https://doi.org/10.3329/dujps.v8i1.5329

Keywords:

Phoenix paludosa, Aracaceae, Lupeol, Epi-Lupeol, ?-sitosterol, Brine shrimp lethality bioassay, Antimicrobial

Abstract

Lupeol (1), epilupeol (2) and β-sitosterol (3) were isolated from the n-hexane and the carbon
tetrachloride soluble fraction of a methanol extract of the leaves of Phoenix paludosa Roxb. The n-hexane, carbon
tetrachloride and chloroform soluble materials from the concentrated methanol extract were subjected to
antimicrobial screening and brine shrimp lethality bioassay. All of the partitionates showed insensitivity to microbial
growth, while the n-hexane, chloroform and methanol soluble fractions showed significant cytotoxicity having LC50
2.17 μg/ml, 2.77 μg/ml and 2.46 μg/ml, respectively. This is the first report of isolation of the compounds 1-3 and
bioactivities of P. paludosa.

Key words: Phoenix paludosa; Aracaceae; Lupeol; Epi-Lupeol; β-sitosterol; Brine shrimp lethality bioassay;
Antimicrobial.

DOI: 10.3329/dujps.v8i1.5329

Dhaka Univ. J. Pharm. Sci. 8(1): 7-10, 2009 (June)

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How to Cite

Alam, F., Rahman, M. S., Alam, M. S., Hossain, M. K., Hossain, M. A., & Rashid, M. A. (2010). Phytochemical and Biological investigations of <i>Phoenix paludosa</i> Roxb. Dhaka University Journal of Pharmaceutical Sciences, 8(1), 7–10. https://doi.org/10.3329/dujps.v8i1.5329

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