Three New Flavonoid Glycosides from the Fruits of Luffa echinata Roxb.- a Hepatoprotective Plant

  • Tanveer Alam Oman?s Medicinal Plants & Marine Natural Products, University of Nizwa, Sultanate of Oman
  • Ahmed Sulaeman Al Harrasi Oman?s Medicinal Plants & Marine Natural Products, University of Nizwa, Sultanate of Oman
  • Bahar Ahmed Antihepatotoxic Research Lab, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Jamia Hamdard, New Delhi-110062
  • Lubna Najam Department of Chemistry, DAV (PG) College, CCS University, Muzaffar Nagar, UP
  • Shah Alam Khan Department of Pharmacy, Oman Medical College, Muscat, Sultanate of Oman
Keywords: Luffa echinata, Cucurbitaceae, Hepatoprotective, Isoscutellarin, Tricetin, Quercetin

Abstract

Phytochemical investigation of bioactive polar extracts of Luffa echinata Roxb. fruits led to the isolation and characterization of three new flavone glycosides viz., 3,5,7,3?,4?-pentahydroxyflavone-3-[-O-?-Dglucopyranosyl- 7-O-?-D-glucopyranoside (1),3,5,7-trihydroxy-(7?,8?- dioxo,9?,10?,-dihydro[a]cyclohex ?13?,(14?), ?11?(12)-12?,13?,-dimethyl)-flavone-7-[-O-?-D-galactopyranosyl-(1?2)]-O-?-D-glucopyranoside (2), and 5,7,8,4?- tetrahydroxy flavone-7-[-O-?-D-xylosyl-(1?2)]-O-?-D-glucopyranoside (3). The structures of the newly isolated compounds were elucidated on the basis of spectral data and chemical evidences.The isolated compounds are found to be new analogs of tricetin, quercetin and isoscutellarin.

Dhaka Univ. J. Pharm. Sci. 15(2): 117-125, 2016 (December)

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Author Biography

Tanveer Alam, Oman?s Medicinal Plants & Marine Natural Products, University of Nizwa, Sultanate of Oman


Published
2017-01-02
How to Cite
Alam, T., Harrasi, A. S., Ahmed, B., Najam, L., & Khan, S. (2017). Three New Flavonoid Glycosides from the Fruits of Luffa echinata Roxb.- a Hepatoprotective Plant. Dhaka University Journal of Pharmaceutical Sciences, 15(2), 117-125. https://doi.org/10.3329/dujps.v15i2.30924
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