Antioxidant, Membrane Stabilizing and Cytotoxic Activities of Cissus adnata (Roxb.)

Authors

  • Ridwan Bin Rashid Department of Microbiology, University of Dhaka, Dhaka-1000
  • Farhan Nur Towsif Department of Pharmacy, State University of Bangladesh, Dhaka-1205
  • Farhana Ahmed Bushra Department of Pharmacy, State University of Bangladesh, Dhaka-1205
  • Faiza Tahia Phytochemical Research Laboratory, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka-1000

DOI:

https://doi.org/10.3329/dujps.v15i1.29198

Keywords:

Cissus adnata, antioxidant, cytotoxic, DPPH

Abstract

The methanol extracts of whole plant of Cissus adnata (Roxb.) and their organic and aqueous soluble partitioning materials were evaluated for antioxidant, cytotoxic and membrane stabilizing properties. In the DPPH free radical scavenging assay, the aqueous extract of whole plant of C. adnata displayed the highest free radical scavenging activity with IC50 value of 4.17 ?g/ml, while the pet ether soluble fraction showed significant lethality to brine shrimps having LC50 value of 1.02 ?g/ml, as compared to the standard vincristine sulphate (LC50 value of 0.44 ?g/ml). In the evaluation for membrane stabilizing property, the pet ether soluble fraction of methanol extract of the whole plant inhibited 67.43 % and 56.60 % hypotonic solution- and heat-induced haemolysis of RBCs, respectively.

Dhaka Univ. J. Pharm. Sci. 15(1): 69-71, 2016 (June)

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Author Biography

Ridwan Bin Rashid, Department of Microbiology, University of Dhaka, Dhaka-1000



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Published

2016-08-08

How to Cite

Rashid, R. B., Towsif, F. N., Bushra, F. A., & Tahia, F. (2016). Antioxidant, Membrane Stabilizing and Cytotoxic Activities of Cissus adnata (Roxb.). Dhaka University Journal of Pharmaceutical Sciences, 15(1), 69–71. https://doi.org/10.3329/dujps.v15i1.29198

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Articles