Antimicrobial Activity of Metal Cystine Complexes

  • Jahan Ara Khanam Department of Biochemistry and Molecular Biology, Rajshahi University, Rajshahi-6205
  • Most. Ferdousi Begum Department of Botany, Rajshahi University, Rajshahi-6205,
  • Jesmine Ara Department of Applied Chemistry and Chemical Technology, Rajshahi University, Rajshahi-6205Dhaka-1000
  • Mele Jesmin BCSIR, Rajshahi-6206,
  • M Abu Taher
  • SM Mohsin Ali Department of Applied Chemistry and Chemical Technology, Rajshahi University, Rajshahi-6205,
Keywords: Antimicrobial activity, Cytotoxic activity, Metal amino acid complexes

Abstract

Metal cystine complexes of nickel(II), mercury(II) and cadmium(II) have been synthesized and their antimicrobial activities have been evaluated. It is found that mercury(II) cystine and cadmium(II) cystine complexes have pronounced antibacterial and antifungal activities. On the other hand nickel(II) cystine shows moderate activities. The LC50 values of nickel(II) cystine, mercury(II) cystine and cadmium(II) cystine are found to be 5.2, 8.0 and 7.2 ?g ml-1, respectively. These values were obtained from cytotoxic studies indicating that they are biologically active compounds. Key words: Antimicrobial activity, Cytotoxic activity; Metal amino acid complexes. Dhaka Univ. J. Pharm. Sci. Vol.5(1-2) 2006 The full text is of this article is available at the Dhaka Univ. J. Pharm. Sci. website

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How to Cite
Khanam, J., Begum, M., Ara, J., Jesmin, M., Taher, M., & Ali, S. (1). Antimicrobial Activity of Metal Cystine Complexes. Dhaka University Journal of Pharmaceutical Sciences, 5(1), 29-32. https://doi.org/10.3329/dujps.v5i1.225
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