Phytochemical and Biological Investigations of <i>Phyllanthus reticulatus</i>

  • Taslima Begum Phytochemical Research Laboratory, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka-1000
  • Mohammad S Rahman Phytochemical Research Laboratory, Department of Pharmaceutical Chemistry, University of Dhaka, Dhaka-1000
  • Mohammad A Rashid Centre for Biomedical Research, University of Dhaka, Dhaka-1000
Keywords: Phyllanthus reticulates, Euphorbiaceae, Scopoletin, Brine shrimp lethality bioassay, Antimicrobial

Abstract

Scopoletin (1) was isolated from the chloroform soluble fraction of a methanol extract of the stem bark of Phyllanthus reticulates (Family: Euphorbiaceae). The petroleum ether, carbon tetrachloride and choloroform soluble fractions of this methanol extract were subjected to antimicrobial screening and brine shrimp lethality bioassay. All of the partitionates showed moderate to strong inhibitory activity to microbial growth while the chloroform soluble fraction showed strongest cytotoxicity having LC50 1.99 ?g/ml. Key words: Phyllanthus reticulates, Euphorbiaceae, Scopoletin, Brine shrimp lethality bioassay, Antimicrobial Dhaka Univ. J. Pharm. Sci. Vol.5(1-2) 2006 The full text is of this article is available at the Dhaka Univ. J. Pharm. Sci. website

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How to Cite
Begum, T., Rahman, M., & Rashid, M. (1). Phytochemical and Biological Investigations of <i>Phyllanthus reticulatus</i&gt;. Dhaka University Journal of Pharmaceutical Sciences, 5(1), 21-23. https://doi.org/10.3329/dujps.v5i1.223
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