Serum levels of Cadmium, Calcium, Lead and Iron in Schizophrenic Patients

  • Pinky Karim Department of Pharmacy, University of Asia Pacific, Dhanmondi, Dhaka
  • Md. Iqbal Hossain Department of Clinical Pharmacy and Pharmacology, Faculty of Pharmacy, University of Dhaka, Dhaka-1000
  • AFM Nazmus Sadat Department of Pharmacy, University of Asia Pacific, Dhanmondi, Dhaka
  • Zabun Nahar Department of Clinical Pharmacy and Pharmacology, Faculty of Pharmacy, University of Dhaka, Dhaka-1000
  • Md. Khalid Hossain Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka-1000
  • Abul Hasnat Department of Clinical Pharmacy and Pharmacology, Faculty of Pharmacy, University of Dhaka, Dhaka-1000
Keywords: Schizophrenic patients, trace elements, clinical significance

Abstract

The serum concentration of cadmium (Cd), lead (Pb), calcium (Ca) and iron (Fe) in 30 schizophrenic patients and 30 normal healthy subjects were analyzed by flame atomic absorption spectroscopy. The concentrations of Cd, Pb and Ca in schizophrenic disorder patients was not increased significantly (P > 0.05) compared to that of the cohort controls. But the concentration of Fe in schizophrenic patients was significantly different from that of the cohort control (p < 0.000). The change in serum concentration of different trace elements may have some prognostic significance for the diagnosis of schizophrenic disorder. However further work is suggested to examine the exact correlation between trace elements level and the degree of disorder in schizophrenic patients. Key words: Schizophrenic patients, trace elements, clinical significance Dhaka Univ. J. Pharm. Sci. Vol.5(1-2) 2006 The full text is of this article is available at the Dhaka Univ. J. Pharm. Sci. website

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Karim, P., Hossain, M., Sadat, A., Nahar, Z., Hossain, M., & Hasnat, A. (1). Serum levels of Cadmium, Calcium, Lead and Iron in Schizophrenic Patients. Dhaka University Journal of Pharmaceutical Sciences, 5(1), 9-13. https://doi.org/10.3329/dujps.v5i1.221
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