TY - JOUR AU - Miah, Md Rubel AU - Rahman, Md Saidur AU - Biswas, Sarmistha AU - Banik, Gobinda Chandra AU - Chowdhury, Md Faizul Islam PY - 2018/07/10 Y2 - 2024/03/28 TI - Cardiovascular Autonomic Dysfunction in Type-2 Diabetes patients with Microalbuminuria in a Tertiary Level Hospital JF - Journal of Medicine JA - J. Medicine VL - 19 IS - 2 SE - Original Articles DO - 10.3329/jom.v19i2.37229 UR - https://www.banglajol.info/index.php/JOM/article/view/37229 SP - 104-109 AB - <p><strong>Background</strong>: Cardiovascular autonomic dysfunction is a serious complication of diabetes mellitus (DM) and is independently associated with microalbuminuria in patients with type-2 DM. This study was conducted to determine the prevalence of cardiovascular autonomic dysfunction in type-2 diabetes patients with microalbuminuria.</p><p><strong>Materials &amp; Methods</strong>: This descriptive type of observational study was done in the department of Medicine, Dhaka Medical College Hospital from August 2015 to January 2016.</p><p><strong>Results</strong>: A total of 50 patients was included in the study with male predominance (M:F ratio 2. 22:1). Peak age was between 40-60 years and majority of patients (32%) was between 41-50 years and mean duration of DM was more than 12 years. Out of 50 patients, 19 (38%) patients had mild microalbuminuria; 24 (48%) patients had moderate microalbuminuria and 7 (14%) patients had severe microalbuminuria. Common symptoms were lethargy, anorexia, nausea, vomiting, dizziness and bladder symptoms. Cardiac autonomic neuropathy (CAN) was found in 80% cases. Parasympathetic dysfunction was observed in 40 (80%) cases and sympathetic dysfunction was observed in 43 (86%) cases.</p><p><strong>Conclusion</strong>: As significant number of DM patients (80%) develop CAN, so cardiovascular autonomic function tests should be monitored to address major potential cardiovascular complications even in asymptomatic patients, especially among those with microalbuminuria.</p><p>J MEDICINE JUL 2018; 19 (2) : 104-109</p> ER -