TY - JOUR AU - Das, Aparna AU - Tarannum, Sanjana AU - Kona, Tahera AU - Saha, Santanu Kumar AU - Kahhar, MA PY - 2015/02/25 Y2 - 2024/03/29 TI - Multicentric Hyaline-Vascular Castleman Disease: A Case Report JF - Journal of Medicine JA - J. Medicine VL - 16 IS - 1 SE - Case Reports DO - 10.3329/jom.v16i1.22402 UR - https://www.banglajol.info/index.php/JOM/article/view/22402 SP - 48-50 AB - <p><em>Castleman disease is a rare lymphoproliferative disorder. Contrary to its closest differential of lymphoma, the disease tends to run a benign course. However the multicentric variety, which is usually of the plasma cell type, has a more sinister prognosis. It is commonly associated with HIV infection. We report a case of a 65 year old man presenting with recurrent episodes of swelling of the whole body and diarrhoea for 3 years. Physical examination revealed generalized lymphadenopathy with hepato-splenomegaly and ascites. Lymph node biopsy revealed histopathological changes consistent with hyaline-vascular type of Castleman disease (multicentric). He was HIV negative. Patient was treated with high dose corticosteroids and discharged with follow up advice.</em></p> <p>DOI: <a href="http://dx.doi.org/10.3329/jom.v16i1.22402">http://dx.doi.org/10.3329/jom.v16i1.22402</a></p> <p>J MEDICINE 2015; 16 : 48-50</p> ER -