Clinical Outcomes of Transpedicular Fixation in Degenerative spondylolisthesis: Evaluation of Back Pain Relief

Abstract

Background: Degenerative spondylolisthesis is a spinal condition associated with aging, primarily occurring at Lumber 4–Lumber 5 (L 4-L 5) in women over the age of 50. Although conservative treatment is typically the first option, surgery is required for ongoing symptoms. Pedicle screw fixation, with or without fusion and decompression, enhances stability, alleviates nerve compression, and boosts pain relief and function, with instrumented fusion typically favored in unstable situations. Objective: This study was done to observe the clinical outcomes of Transpedicular Fixation in degenerative spondylolisthesis. Materials and Method: This observational study was carried out from 2020 to 2024 at Dhaka Medical College Hospital and Green Life Hospital,Dhaka,Bangladesh, involving 175 patients with degenerative spondylolisthesis who underwent transpedicular fixation. Pain and function were evaluated using Visual Analogue Scale (VAS) and Oswestry Disability Index (ODI) before surgery and at 3 and 6 months after surgery. Both ethical approval and informed consent were secured. Results: In total, 175 patients (average age 57.2 ± 10.1 years; 61.7% female) with mainly Grade I spondylolisthesis were recruited. After transpedicular fixation, pain and function showed notable enhancement, with VAS decreasing from 7.7 ± 1.2 to 2.2 ± 0.9 and ODI declining from 59.1 ± 9.3 to 19.6 ± 6.2 at the 6-month mark (p < 0.001). At the final follow-up, 88% of patients reached good to excellent results. Postoperative complications were observed in 12.6%, with superficial wound infection being the most frequent, and no deaths recorded Conclusion: Transpedicular fixation for degenerative spondylolisthesis offers substantial pain alleviation and enhancement in function, yielding high rates of favorable to excellent results. It is a reliable and efficient choice with manageable complications in chosen patients.

J Med Coll Women Hosp.2026; 22(2): 219-225