Case Report of a Boy Presented With Brown Nappy

Authors

  • Shammi Akter Assistant Registrar of Pediatric Nephrology, Chittagong Medical College Hospital, Chattogram.
  • Mohammed Maruf-ul Quader Associate Professor of Pediatric Nephrology, Chittagong Medical College, Chattogram.
  • Utpal Sen Assistant Professor of Ophthalmology, Chittagong Medical College, Chattogram.
  • A K M Rezaul Karim Professor of Pediatrics and Pediatric Hematology, Chittagong Medical College, Chattogram.

DOI:

https://doi.org/10.3329/jcmcta.v34i2.83632

Keywords:

Alkaptonuria; Brown nappy; Homogentisic acid.

Abstract

Background: Alkaptonuria is a rare tyrosine metabolism disorder due to a deficiency of the enzyme Homogentisic Acid Oxidase (HGO) and it carries autosomal recessive inheritance. We report this case, for increasing awareness among the doctor’s society, so that early diagnosis of diseases from urine color.

Case Presentation: A 14-month-old boy, 2nd issue of a consanguineous couple brought to Outpatient Department of Paediatric Nephrology with symptoms of staining of nappy following urination on 1st March 2022. His urine chromatography report shows a high concentration of homogentisic acid and later diagnosed with a case of alkaptonuria.

Conclusion: Alkaptonuria has to be considered if any child presents with darkening of urine exposure to the atmosphere. Early identification of diseases would be beneficial for delaying potential complications.

JCMCTA 2023 ; 34 (2) : 150-152

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Published

2025-08-25

How to Cite

Akter, S., Quader, M. M.- ul, Sen, U., & Karim, A. K. M. R. (2025). Case Report of a Boy Presented With Brown Nappy. Journal of Chittagong Medical College Teachers’ Association, 34(2), 150–152. https://doi.org/10.3329/jcmcta.v34i2.83632

Issue

Vol. 34 No. 2 (2023)

Section

Case Reports