Journal of Current and Advance Medical Research 2021-04-04T06:46:57+00:00 Dr. M. Abdullah Yusuf Open Journal Systems <p>Official journal of Bangladesh Doctors Society. Articles in the Journal of Current and Advance Medical Research are Open Access articles published under the Creative Commons CC BY-NC License (<a href=""></a>). This license permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.</p> <p>JCAMR is included in the <a title="NLM" href="" target="_blank" rel="noopener">NLM Catalog</a> ID:101673828</p> Prons and Cons of Covid19 Vaccination: Bangladesh Perspectives 2021-04-04T06:46:24+00:00 AFM Arshedi Sattar <p>No Abstract is available</p> 2021-03-15T00:00:00+00:00 Copyright (c) 2021 AFM Arshedi Sattar Profiles of Breast Diseases among Women Seeking for Treatment during Covid-19 Pandemic at Surgery OPD of Medical University of Bangladesh 2021-04-04T06:46:25+00:00 Bidyut Chandra Debnath Abanti Ghosh Abul Kalam Chowdhury Rana Jahangir Ferdous Alam Aminul Islam Joardar AHM Towhidul Alam <p><strong>Background:</strong> Different pathology of breast is found among the women.</p> <p><strong>Objective: </strong>The purpose of the present study was to see the profiles of breast disease among women seeking for treatment during Covid-19 pandemic at the OPD of medical university of Bangladesh.</p> <p><strong>Methodology: </strong>This descriptive cross-sectional study was conducted in the Department of Surgery at Bangabandhu Shiekh Mujib Medical University, Dhaka, Bangladesh from 1 April to 31 October 2020 for a period of six months. All the women who were attended at the OPD of the Department of Surgery with the different complaints of breast at any age were selected as study population. The different disease profiles were recorded in the data sheet.</p> <p><strong>Result:</strong> A total number of 1625 women were recruited for this study. The mean age with standard deviation of the study population was 36.4±12.54 years. Among 1492 women the most common breast complaints was mastalgia which was 492(29.9%) cases followed by fibrocystic disease, breast lump, fibroadenoma and carcinoma breast which was 296(18.0%) cases, 202(12.3%) cases, 141(8.6%) cases and 84(5.1%) cases respectively. Similarly duct ectasia, fibroadenoma, fibrocystic disease and lipoma were also most common among the less than or equal to 45 years age group of women which were 47(94.0%) cases, 137(97.2%) cases, 269(90.9%) cases and 75(51.4%) cases respectively.</p> <p><strong>Conclusion: </strong>In conclusion breast lump and fibrocystic disease are the most common diseases among the women attending during covid19 era.</p> <p><em>Journal of Current and Advance Medical Research, January 2021;8(1):3-6</em></p> 2021-03-15T00:00:00+00:00 Copyright (c) 2021 Bidyut Chandra Debnath, Abanti Ghosh, Abul Kalam Chowdhury, Rana Jahangir, Ferdous Alam, Aminul Islam Joardar, AHM Towhidul Alam Comparison of Maternal Outcomes between Clinical and Subclinical Hypothyroid Pregnant Women admitted in a Subspecialty Department of a Tertiary Hospital 2021-04-04T06:46:27+00:00 Farzana Sharmin Mahfuja Asma Sanzida Mahmud Afzal Momin Tripti Rani Das Firoza Begum <p><strong>Background: </strong>Women with Hypothyroidism have higher pregnancy complication rates.</p> <p><strong>Objective: </strong>The purpose of the present study was to compare the effects of clinical and subclinical hypothyroidism on maternal outcomes.</p> <p><strong>Methodology: </strong>This cohort study was conducted in the Feto-Maternal Department of&nbsp; Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh from a period of 6 months dated from September 2019 to February 2020 for a period of 6 months. All cases of the clinical and sub-clinical hypothyroid pregnant women admitted in this department. Maternal outcomes of both groups during pregnancy were recorded. Findings of the cases recorded carefully.</p> <p><strong>Result: </strong>This study was conducted among 75 patients, which was 14.79% of the total admitted cases during study period. Maximum (62.79%) number was found in the age group of 25 to 44 years in group I and 65.62% cases in group II.&nbsp; (p&lt;0.05). Severe Pre Eclampsia was observed 2(4.65%) cases and 6(18.75%) Group II. Abruptio placenta was observed 5(15.62%) cases in group II and none in group I. However Preterm delivery are three times more 39.5% in group I cases. Uterine rupture, abortion are&nbsp; &nbsp;observed only in group II patients (p&lt;0.05).</p> <p><strong>Conclusion: </strong>In conclusion maternal outcomes are significantly varied in clinical and subclinical hypothyroidism women during pregnancy.</p> <p><em>Journal of Current and Advance Medical Research, January 2021;8(1):7-11</em></p> 2021-03-15T00:00:00+00:00 Copyright (c) 2021 Farzana Sharmin, Mahfuja Asma, Sanzida Mahmud, Afzal Momin, Tripti Rani Das, Firoza Begum Risk Factors and Primary Diseases Responsible for Acute Kidney Injury among Neonates 2021-04-04T06:46:29+00:00 Sharmin Akter Luna Syma Akter Tahmina Jesmin Syed Saimul Haque Golam Muin Uddin Ranjit Ranjan Roy <p><strong>Background: </strong>There are several risk factors and diseases related with the acute kidney injury among neonates.</p> <p><strong>Objective:</strong> The purpose of the present study was to find out the risk factors and primary disease responsible for acute kidney injury among neonates.</p> <p><strong>Methodology: </strong>This cross-sectional study was conducted in the Department of Paediatric Nephrology at Bangabandhu Sheikh Mujib University, Dhaka, Bangladesh from May 2018 to July 2019 for a period of one year. Patients with the age group of less than 1 months who were at risk of AKI, and admitted in the inpatient department of Pediatrics and allied at Bangabandhu Sheikh Mujib University, Dhaka, Bangladesh in both sexes were selected as study population. To detect AKI, serum creatinine was measured at 0 h (baseline), 48 h and 5<sup>th</sup> day respectively.</p> <p><strong>Result: </strong>A total number of 52 patients who fulfilled the inclusion criteria were enrolled in this study. Among them 10 cases were in neonatal age group. The mean age was 10.8±5.4 days with female predominance. The risk factors of AKI in neonate was only pre-renal; mostly due to hypovolemia which was 3(60.0%) cases followed by sepsis and asphyxia which were 1(20.0%) case in each. The most patients had sepsis which was 4(40.0%) cases followed by congenital heart disease which was 2(20.0%) cases; one presented with heart failure and another one had cyanotic congenital heart disease.</p> <p><strong>Conclusion:</strong> In conclusion hypovolemia, sepsis and asphyxia are the most common risk factors of acute kidney injury among the neonates.</p> <p><em>Journal of Current and Advance Medical Research, January 2021;8(1):12-16</em></p> 2021-03-15T00:00:00+00:00 Copyright (c) 2021 Sharmin Akter Luna, Syma Akter, Tahmina Jesmin, Syed Saimul Haque, Golam Muin Uddin, Ranjit Ranjan Roy Effect of Aegle Marmelos Fruit Pulp Powder on Chronic Subclinical Inflammatory Status (Phase 3 clinical trial) of Type 2 Diabetic Patients 2021-04-04T06:46:31+00:00 Murshida Aziz Rupali Debnath Tohfa E Ayub Fahmida Islam Farjana Aktar Safwanul Aman <p><strong>Background:</strong> The plant is reported to have multiple therapeutic properties such as chronic subclinical inflammation.</p> <p><strong>Objective:</strong> In this present study <em>Aegle marmelos</em> was investigated for its anti-inflammatory effects on human T2DM subjects.</p> <p><strong>Methodology:</strong> The present study was conducted at Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM), Dhaka, Bangladesh from July 2010 to June 2011 to explore the effect of <em>Aegle marmelos</em> unripe fruit pulp on chronic subclinical inflammatory status in T2DM patients as evident by hsCRP. It was an un-blinded clinical trial conducted under a cross-over design. The experiment was conducted under a crossover design and the effects were analyzed during the 0-21 as well as 28-49 days with 7 days wash out period. The data were then pooled and the baseline versus endpoint values was also compared.</p> <p><strong>Result: </strong>The mean blood hsCRP values did not significantly differ between the intervention and control groups at any time points. &nbsp;No significant difference between the baseline and end point values regarding blood hsCRP. The effect on blood hsCRP was not significant in any of the analysis.</p> <p><strong>Conclusion:</strong> This study reveals no changes in chronic subclinical inflammatory status of <em>Aegle marmelos</em> fruit pulp in T2DM patients.</p> <p>Journal of Current and Advance Medical Research, January 2021;8(1):17-20</p> 2021-03-15T00:00:00+00:00 Copyright (c) 2021 Murshida Aziz, Rupali Debnath, Tohfa E Ayub, Fahmida Islam, Farjana Aktar, Safwanul Aman Disease Profiles of Head and Neck Lesions Diagnosed by Fine Needle Aspiration Cytology at a Tertiary Care Hospital in Bangladesh 2021-04-04T06:46:33+00:00 Kazi Md. Shahidur Rahman Md. Mahmudul Huda ASM Mahmud Hasan Md Shaheeduzzaman Gazi Manjurul Islam <p><strong>Background: </strong>Head &amp; Neck lesions encompass a multitude of congenital, inflammatory or neoplastic lesions including several anatomic sites and originating in different tissues and organs. FNAC is a simple, quick, feasible, cost effective and repeatable outpatient procedure with minimum risk of complications.</p> <p><strong>Objective: </strong>The purpose of the present study was to study the spectrum of head &amp; neck lesions attending in outpatient.</p> <p><strong>Methodology: </strong>This present cross-sectional study included the patients presented with palpable head &amp; neck swelling from January 2018 to September 2019 in outpatient (mostly ENT &amp; HNS OPD) department of Monno Medical College &amp; Hospital, Monno City, Gilondo, Manikgonj. Aspirates were done using mostly 5ml syringe and 23-gauge needle. Smears were stained with Papanicolaou stain.</p> <p><strong>Results: </strong>Out of 210 patients of head &amp; neck lesions studied, Lymph node (50.47%) was the predominant site aspirated with chronic nonspecific lymphadenitis &amp; lymphoid hyperplasia being the commonest lesion. Thyroid lesions constituted 31.90% cases followed by soft tissue (11.9%) and salivary gland (5.71%).</p> <p><strong>Conclusion: </strong>In conclusion FNAC is simple, quick, inexpensive and minimally invasive technique to diagnose different types of head and neck swelling. It could differentiate the infective process from neoplastic one and avoid unnecessary surgeries.</p> <p><em>Journal of Current and Advance Medical Research, January 2021;8(1):21-24</em></p> 2021-03-15T00:00:00+00:00 Copyright (c) 2021 Kazi Md. Shahidur Rahman, Md. Mahmudul Huda, ASM Mahmud Hasan, Md Shaheeduzzaman, Gazi Manjurul Islam Biochemical Changes in Neonates with and without Seizure: A Comparative Study 2021-04-04T06:46:35+00:00 ASM Shahidullah Rafika Afrose Kalpona Deb Bina Sen Arup Ratan Paul Kamona Rani Saha Nilufar Begum <p><strong>Background:</strong> Seizure is a common neurological disorder in the pediatric age group.</p> <p><strong>Objective:</strong> Neonates with seizure have decreased in serum calcium, magnesium, sodium, potassium, and glucose if compared to neonates without seizure.</p> <p><strong>Methodology:</strong> This comparative cross-sectional study was carried out in the Department of Biochemistry at Mymensingh Medical Collage, Mymensingh, Bangladesh in cooperation with the Department of Pediatric of Mymensingh Medical Collage &amp; Hospital, Mymensingh, Bangladesh from July 2005 to June 2006. Neonates were included in the study. Subjects were divided into two groups designated as group I as control group and group II cases. From each subject at least 2 ml of blood were collected from femoral vein and was collected serum for biochemical analysis.</p> <p><strong>Result: </strong>A total of 60 neonates were included in the study. Subjects were divided into two groups-group-I control- (n=20) and group II cases-(n=40). The concentration of serum calcium, magnesium, sodium, potassium, and glucose yielded 7.33 ±0.79, 5.79 ±1.10; 2.18 ± 0.23,1.61 ± 0.25; 134.82 ±3.03, 133.68±8.57; 4.80 ±0.56,5.89 ±2.02; 66.33 ± 8.23, 62.25± 7.96 in group I and group II respectively.</p> <p><strong>Conclusion</strong>: Significant decreases of serum calcium, magnesium and significant increase of serum potassium in neonates with seizure are found in this study. The change in serum sodium and glucose are not significant<strong>. </strong></p> <p><em>Journal of Current and Advance Medical Research, January 2021;8(1):25-29</em></p> 2021-03-15T00:00:00+00:00 Copyright (c) 2021 ASM Shahidullah, Rafika Afrose Appraisal of the Current Pharmacology Curriculum, Teaching Methodology and Effectiveness in Undergraduate Medical Education: A Student-Centric, Questionnaire-Based Study 2021-04-04T06:46:37+00:00 Sujit Kumar Sarker Geethanjali Bhas Priyanka Moitra Ratna Paul Md. Abdullah Yusuf Vijaya Marakala Zubair Ahmed Ratan Ikramul Ahmed Khan Mohammad Arif AM Selim Reza <p><strong>Background</strong>: Periodic students’ feedback ensures and enhances the effectiveness of the curriculum of medical subject.</p> <p><strong>Objective</strong>: This study was designed to obtain students appraisal of the undergraduate pharmacology curriculum and teaching methodology.</p> <p><strong>Methodology:</strong> This cross-sectional study was conducted in the Department of Pharmacology at Colonel Malek Medical College, Manikganj, Bangladesh from May to June, 2019 for a period of two months. Questionnaire-based data were collected from students of both sexes who had completed 3rd Professional examination. Likert Scale was applied to collect students’ feedback on pharmacology.</p> <p><strong>Results:</strong> A total number of 40 students were recruited for this study of which 60.0% students were strongly agreed about organized teaching. About 47.5% students were agreed that the course was appropriate at their level and achieved their goals in Pharmacology. However, 55% of them strongly agreed that teacher provided clear constructive feedback during class. Total 60%, were agreed that the course improved their problem-solving skills. Overall, 55% students were agreed regarding their satisfaction on Pharmacology course delivery and conduction.</p> <p><strong>Conclusion</strong>: In conclusion, periodic appraisal from students regarding evaluation of the student-centric undergraduate pharmacology curriculum is vital in developing efficient medical graduates.</p> <p><em>Journal of Current and Advance Medical Research, January 2021;8(1):30-33</em></p> 2021-03-15T00:00:00+00:00 Copyright (c) 2021 Sujit Kumar Sarker Diagnostic Validity of Ratio between Differences of Central Venous to Arterial CO2 and Arterial to Central Venous O2 Content in Diagnosis of Anaerobic Metabolism among Septic Patients 2021-04-04T06:46:39+00:00 Subroto Kumar Sarker Umme Kulsum Choudhury Mohammad Mohsin Subrata Kumar Mondal Muslema Begum <p><strong>Background: </strong>Detection of anaerobic metabolism is very crucial for the management of the septic patients.</p> <p><strong>Objective: </strong>The purpose of the present study was to validate the ratio between differences of central venous to arterial CO<sub>2</sub> and arterial to central venous O<sub>2 </sub>content in diagnosis of anaerobic metabolism among septic patients.</p> <p><strong>Methodology: </strong>This prospective observational study was conducted in the Intensive Care Unit of the department of Anaesthesia Analgesia, Palliative and Intensive Care Medicine at Dhaka Medical College Hospital, Dhaka, Bangladesh from January 2016 to December 2016. All patients admitted to ICU with the features of severe sepsis and septic shock according to SSC guidelines with the age of more than or equal to 18 years in both sexes were included in this study. The arterial and central venous blood gases were measure simultaneously. At the same time serum lactate was measured.</p> <p><strong>Result: </strong>Among the 69 patients, 31(44.9%) were of severe sepsis and 38(55%) were of septic shock patients. In the severe sepsis and septic shock patients the mean P(v-a)CO<sub>2</sub>/C(a-v)O<sub>2 </sub>is 1.39±0.41 and 1.11±0.40 respectively. Serum lactate in case of severe sepsis and septic shock patients is 2.85±1.40 and 3.85±1.04 respectively. The ROC analysis showed an area under curve 0.89 and P(v-a)CO<sub>2</sub>/C(a-v)O<sub>2 </sub>ratio cutoff value of 1.21 showed sensitivity 0.84 and specificity 0.94.</p> <p><strong>Conclusion: </strong>The P(v-a)CO<sub>2</sub>/C(a-v)O<sub>2 </sub>&nbsp;ratio is also a another marker of global anaerobic metabolism and it would be used for diagnosis as well as management of septic patient.&nbsp;</p> <p><em>Journal of Current and Advance Medical Research, January 2021;8(1):34-38</em></p> 2021-03-20T00:00:00+00:00 Copyright (c) 2021 Subroto Kumar Sarker Serum Hemoglobin Level in Preeclampsia 2021-04-04T06:46:41+00:00 Selina Akhtar Umme Hafsa Any Sonia Fahmi <p><strong>Background: </strong>Pre-eclampsia is the major cause of maternal and fetal mortality and morbidity. It affects approximately 5-8% of pregnant women.</p> <p><strong>Objectives</strong>: The study was undertaken to find an association between Hemoglobin and preeclampsia.</p> <p><strong>Methodology:</strong> This cross-sectional study was carried out in the Department of Physiology at Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka, Bangladesh from July 2009 to June 2010. For this, 60 pregnant women of preeclampsia, age ranged from 18 to 39 years, more than 20th weeks of pregnancy were included in the study (group B). They were further divided into group B<sub>1</sub> consisting of 30 mild preeclamptic women and group B<sub>2</sub> consisting of 30 severe preeclamptic women. For comparison age and gestational period matched 30 normotensive pregnant women control (group A) were also studied. Both control (group A) and preeclamptic women were selected from Obstetric and Gynae in and out patient Department of BSMMU and Dhaka Medical College Hospital. Maternal hemoglobin concentration was measured by standard laboratory techniques.</p> <p><strong>Result: </strong>In this study, hemoglobin levels were significantly higher in study (group B) than those of control (group A). Again Hemoglobin levels were higher in group B<sub>2</sub> than B<sub>1,</sub> but not significant (P&gt;0.05). Hemoglobin level was positively correlated with systolic and diastolic blood pressure but it was statistically non-significant (P&gt;0.05).</p> <p><strong>Conclusion: </strong>The study concluded that serum hemoglobin level is associated with preeclampsia.</p> <p><em>Journal of Current and Advance Medical Research, January 2021;8(1):39-43</em>]</p> 2021-03-20T00:00:00+00:00 Copyright (c) 2021 Selina Akhtar Immediate Appearance of Different Clinical Features Depending On the Serum Potassium level among Acute Gastroenteritis Children: A Hospital Based Study 2021-04-04T06:46:43+00:00 Nevis Wadia AFM Salim Nobo Krishna Ghosh Gouri Saha Aditi Chowdhury Sayeema Kabir <p><strong>Background:</strong> Serum potassium is a very sensitive serum electrolytes.</p> <p><strong>Objective:</strong> The purpose of the present study was to see the immediate appearance of different clinical features among children depending on the serum potassium level.</p> <p><strong>Methodology: </strong>This cross-sectional study was conducted in the Department of Pediatric Medicine at Institute of Child Health (ICH), Mirpur, Dhaka, Bangladesh from September 2011 to February 2012. Every consecutive child with both sexes admitted with acute watery diarrhea and vomiting of less than 14 days duration were enrolled in this study. The clinical manifestations that were observed in this study were neck flop, weakness of limbs, abdominal distention, diminished or absent bowel sounds. Serum potassium was measured from the venous blood.</p> <p><strong>Result: </strong>A total number of 126 children were recruited for this study. Majority of the children (64.3%) were 2 to 12 months old followed by 13 to 24 months old children (27.0%). The abdominal distension was first developed at potassium level 3.4 mmol/L and highest number of patient developed this feature at potassium level 3.2 mmol/L. The neck flop was first developed at potassium level 3.4 mmol/L and highest number of patient developed this feature at potassium level 3.0 mmol/L. The diminished or absent bowel sound was first developed at potassium level 3.4 mmol/L.</p> <p><strong>Conclusion:</strong> In conclusion abdominal distension, neck flop, diminished/absent bowel sound and muscular weakness are developed immediately after the changes of serum potassium level among the children presented with acute gastroenteritis.</p> <p><em>Journal of Current and Advance Medical Research, January 2021;8(1):44-48</em></p> 2021-03-23T00:00:00+00:00 Copyright (c) 2021 Nevis Wadia, AFM Salim, Nobo Krishna Ghosh, Gouri Saha, Aditi Chowdhury, Sayeema Kabir Indications of Preterm Caesarean Section: Experience of 100 Cases at a Tertiary Care Hospital in Bangladesh 2021-04-04T06:46:45+00:00 Rebeka Khanam Fatema Mahbooba Akter Rabeya Parvin Lutfunnahar Shampa <p><strong>Background: </strong>Preterm caesarean section is performed for different indication among the pregnant women.</p> <p><strong>Objective: </strong>The purpose of the present study was to find out the indications of preterm caesarean section among pregnant women.</p> <p><strong>Methodology: </strong>This cross sectional study was conducted in the Department of Obstetric &amp; Gynaecology at Shaheed Ziaur Rahman Medical College Hospital, Bogra, Bangladesh from January 2007 to December 2007 for a period of one year. Women with the gestational age between 32 to 36 completed weeks who were selected for delivery by Caesarean section were selected as study population. All the women of study were assessed on the basis of detailed history, clinical examination, gestational period, history of premature rupture of membranes, any vaginal bleeding and fetal condition.</p> <p><strong>Result: </strong>A total number of 100 pregnant women were recruited for this study. In this study most of the pregnant women were in the age group of15 to 20 years which was 40(40.0%) cases followed by the age group of 21 to 25 years which were 20(20.0%) cases. About 43(43.0%) cases were complicated with pregnancy induced hypertension. Almost all of them had indication for immediate caesarean section. Among the group incidence of eclampsia was high which was in 23(23.0%) cases; however, preeclampsia was found in 20(20.0%) cases. Ante partum haemorrhage was reported in 10(10.0%) cases. Pregnant women with premature rupture of membrane (PROM) was found in 14(14.0%) cases; furthermore, PROM with Chorioamnionitis was detected in 5(5.0%) cases. Preterm labour with history of previous caesarean section was given by 5(5.0%) women.</p> <p><strong>Conclusion:</strong> In conclusion eclampsia and preeclampsia are the most common indication for preterm caesarean section followed by premature rupture of membrane.</p> <p><em>Journal of Current and Advance Medical Research, January 2021;8(1):44-48</em></p> 2021-03-23T00:00:00+00:00 Copyright (c) 2021 Rebeka Khanam, Fatema Mahbooba Akter, Rabeya Parvin, Lutfunnahar Shampa Incidence of Infective Endocarditis among Haemodialysis Patients: Experience at a Single Centre in Bangladesh 2021-04-04T06:46:47+00:00 Md. Zakir Hussain Muhammad Rafiqul Alam Muhammad Abdur Razzak Mohammad Ehasun Uddin Khan <p><strong>Background</strong>: Infection in hemodialysis is a very dangerous condition for the patients<strong>. </strong></p> <p><strong>Objective: </strong>The purpose of the present study was to find out the incidence of infective endocarditis among hemodialysis patients.</p> <p><strong>Methodology: </strong>This was a cross sectional study which was conducted in the Department of Nephrology at Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh during the periods of July 2010 and June 2012. Hemodialysis patients who were attending in the Department of Nephrology at BSMMU, Dhaka were taken as study population.</p> <p><strong>Results</strong>: A total number of 50 patients presented with hemodialysis. Out of 50 patients 34(68.0%) cases were male and 16(32.0%) cases were female. The mean with SD of age of the patients was 38.44±13.0 years with a range of 18 to 68 years. Out of 50 patients 6(12.0%) cases had positive blood culture of which 3 cases had shown <em>Staphylococcus aureus</em>, 1 case had <em>Escherichia coli</em>, 1 case had <em>Enterococci </em>species and 1 case had Salmonella typhi, Among the 50 patients 5 (10.0%) had vegetation on cardiac valve. The patients frequency of dialysis 2 times per week showed 01 (2.43%) positive blood C/S and 5 positive in 3 times per week showed 05 (55.55%) positive blood C/S (p&gt;0.001).</p> <p><strong>Conclusion:</strong> In conclusion infective endocarditis causes infection with high mortality among the patients of CKD undergoing hemodialysis.</p> <p><em>Journal of Current and Advance Medical Research, January 2021;8(1):54-58</em></p> 2021-03-23T00:00:00+00:00 Copyright (c) 2021 Md. Zakir Hussain, Muhammad Rafiqul Alam, Muhammad Abdur Razzak, Mohammad Ehasun Uddin Khan Immunophenotypic Pattern and Treatment Outcome after Completion of Induction Remission in Children with Acute Lymphoblastic Leukemia 2021-04-04T06:46:49+00:00 Farah Diba Md. Anwarul Karim Shahinoor Akter Soma Indira Chowdhury Showkat Mamun Md. Nazrul Islam Mondal <p><strong>Background</strong>: Acute lymphoblastic leukemia (ALL) is presented with different immunophenotypic pattern.</p> <p><strong>Objective:</strong> The purpose of the study was to evaluate the immunophenotypic pattern of ALL and also, to recognize the frequency of different ALL subtypes and treatment outcome after induction remission therapy.</p> <p><strong>Methodology:</strong> This prospective study was conducted in the Department of Paediatric Hematology and Oncology at Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh from June 2017 to July 2018 for a period of one year. Newly diagnosed admitted cases of ALL aged 1 to 17.9 years were included. Immunophenotyping from aspirate marrow samples were done in a special hematology laboratory. Patients were monitored during induction remission period with physical examination and required investigations.</p> <p><strong>Result</strong>: Among 87 analyzed patients, 81 patients (93.1%) were B-cell ALL and 6 patients (6.9%) were T-cell ALL. After completion of induction remission therapy 61 patients had undergone complete remission and among them B cell ALL were 56(69.1%) and T cell were 5(83.3%) (P=0.464). None of the patient had partial response or induction failure. Complication were developed in 53(60.91%) patients during induction therapy. Most common cause of death was septicemia (22/26). Death was more in patients who had total WBC count &gt;50X10<sup>9</sup>/L (p=0.017) and received regimen B (p=0.031).</p> <p><strong>Conclusion:</strong> B cell ALL was more common and most of the patients had undergone complete remission after induction remission therapy.</p> <p><em>Journal of Current and Advance Medical Research, January 2021;8(1):59-64</em></p> 2021-03-23T00:00:00+00:00 Copyright (c) 2021 Farah Diba, Md. Anwarul Karim, Shahinoor Akter Soma, Indira Chowdhury, Showkat Mamun, Md. Nazrul Islam Mondal Surgical Outcomes of Temporary Ileostomy Patients attended at a Tertiary Care hospital in Dhaka City 2021-04-04T06:46:51+00:00 Muhammad Faridul Haque SM Syeed-Ul-Alam Ayesha Rahman Md. Mahfuzur Rahman Khan Muhammad Enamul Haque <p><strong>Background:</strong> Management of temporary ileostomy cases is very important considering the outcomes.</p> <p><strong>Objective: </strong>The purpose of the present study was to observe the surgical complications of temporary ileostomy patients.</p> <p><strong>Methodology:</strong> This prospective cohort study was conducted in the Department of Surgery at Sir Salimullah Medical College &amp; Mitford Hospital, Dhaka, Bangladesh over a period of six months from July, 2011 to December, 2011. All patients who had undergone temporary ileostomy after admission were selected as the study population. Patients with temporary ileostomy at any age in both male and female were included in this study. The surgical complications like prolapse, retraction, stenosis, necrosis, skin excoriation, parastomal hernia, bleeding and wound infection were recorded<strong>.</strong></p> <p>&nbsp;</p> <p><strong>Result: </strong>A total number of 100 patients were selected for observation and management of complications of temporary ileostomy. Their ages ranging from 15 to 65 years with mean age 33.9±11.92 years. Complications were developed in majority cases of cases (52.0%). Several systemic complications were recorded like electrolytes imbalance (31%), hypoproteinaemia (14%), RTI (6%) and significant weight loss (4%). Skin excoriation was the more frequent local complication developed in 32 (32%) patients. However, 36 patients developed laparotomy wound related complication.</p> <p><strong>Conclusion: </strong>In conclusion high frequency of complications are found among the temporary ileostomy patients.</p> <p><em>Journal of Current and Advance Medical Research, January 2021;8(1):65-69</em></p> 2021-03-31T00:00:00+00:00 Copyright (c) 2021 Muhammad Faridul Haque, SM Syeed-Ul-Alam, Ayesha Rahman, Md. Mahfuzur Rahman Khan, Muhammad Enamul Haque Nephron-Sparing Laparoscopic versus Open Surgery for T1 Renal Mass: Seven Years’ Experience and Outcomes 2021-04-04T06:46:53+00:00 Md. Waliul Islam Md. Fazal Naser Md. Abul Hossain Md. Muazzam Hossan BM Saiduzzaman Mominul Haider <p><strong>Background:</strong> Nephron-sparing surgery is an accepted treatment modality for renal cell carcinoma (RCC) in certain situations.</p> <p><strong>Objectives:</strong> The aim of this study was to compare perioperative outcomes after laparoscopic and open partial nephrectomy for patients with a solitary renal tumors of 7cm or less in different institutes in Dhaka.</p> <p><strong>Methodology:</strong> Between June 2013 and October 2020, 23 patients had undergone LPN and 24 patients had undergone OPN for the treatment of solitary renal tumors of 7cm or less in different institutes in Dhaka. Large renal mass (&gt;7cm), multiple tumor and patients with complex renal anatomy were excluded from this study. Patients having previous abdominal surgery were excluded from LPN and all LPN were performed transperitoneally.</p> <p><strong>Results:</strong> Although the mean operative time was longer in the LPN than in the OPN group (134.4±35.36 (45-180) minutes versus 110.56±35.36 (60-165) minutes; P&lt;0.001), the blood loss was comparable between the two groups (130 mL versus 180 mL; P value is not statistically significant). No blood transfusions were performed in either group. The hospital stay was significantly reduced after LPN compared with after OPN (2.8 days (2-6) versus 6.7 days (5-8); P &lt;0.0002). 2 patients in LPN and 1 patient in OPN had positive surgical margins.</p> <p><strong>Conclusion:</strong> This study has revealed that LPN is a feasible and safe alternative to the OPN with better surgical outcomes and similar oncological outcomes.</p> <p><em>Journal of Current and Advance Medical Research, January 2021;8(1):70-74</em></p> 2021-03-31T00:00:00+00:00 Copyright (c) 2021 Mohammad Abdullah Yusuf A Case Presentation and Treatment Review on Novel COVID 19 2021-04-04T06:46:55+00:00 Ambika Nand Jha Akshay H Shah Upama N Trivedi <p>SARS-COV 2 Is causative agent of COVID 19, just few month&nbsp;ago was foreign to us and now spreading its routes well in India. Starting with one case&nbsp;As of August 25, 2020 in India 3167323&nbsp;positive cases have been reported. coronavirus is beta form&nbsp; of SARS-CoV-2 belong to family of Coronaviridae. A 44-year-old man, who lives in Kolakata, West Bengal, Working in a travel agency. He came To OPD with complaint of fever, Throat Infection, Multiple joint and muscle pain, Cough. A SARS-CoV-2 Reverse transcriptase polymerase chain reaction (RTPCR) test was positive. He was being treated &amp; Monitored in Home isolation&nbsp;with high dose oral ascorbic acid, hydroxychloroquine, azithromycin and Zinc acetate. This Article aimed to Case Presentation And Treatment Review of Novel COVID 19.</p> <p><em>Journal of Current and Advance Medical Research, January 2021;8(1):75-77</em></p> 2021-03-31T00:00:00+00:00 Copyright (c) 2021 Ambika Nand Jha, Akshay H Shah, Upama N Trivedi