Coagulation Impairment in Type 2 Diabetes Mellitus

Authors

  • Fayeza Karim Assistant professor, Department of Physiology, Aichi Medical College, Uttara, Dhaka
  • Qazi Shamima Akter Professor and Head, Department of Physiology, Dhaka medical college, Dhaka
  • Shamima Jahan Assistant professor, Department of Physiology, Central Medical College, Comilla
  • Afruza Khanom Assistant professor, Department of Physiology, Marks Medical College, Dhaka
  • Samira Haque Medical officer, Dhaka medical College, Dhaka
  • Tania Yeasmin Assistant professor, Department of Physiology, East West Medical College, Uttara, Dhaka
  • Tashfia Siddika Lecturer, Department of Physiology, Shaheed Suhrawardi Medical College, Dhaka
  • Susmita Sinha Assistant professor, Department of Physiology, Estern Medical College, Comilla

DOI:

https://doi.org/10.3329/jbsp.v10i1.24614

Keywords:

Prothromin time, Activated partial thromboplastin time, cardiovascular disease, diabetes mellitus

Abstract

Background: Complication of diabetes mellitus (DM) includes coagulation impairment. Hypercoagulable state in patient with DM may accelerate thromboembolic risk for cardiovascular disease (CVD).

Objective: To assess Prothrombin Time and Activated Partial Thromboplastin Time in type 2 diabetes mellitus for observing their coagubility status.

Methods: This cross sectional study was conducted in the Department of Physiology, Dhaka Medical College, Dhaka from July 2013 to June 2014. One hundred male patients with type 2 diabetes mellitus aged 40-60 years and one hundred age, BMI matched healthy subjects were included as control in this study. Patients were selected from BIRDEM, Dhaka. Prothrombin Time (PT), Activated Partial Thromboplastin Time (APTT) were estimated by auto analyzer. For statistical analysis unpaired studentt test was used.

Results: In this study PT and APTT were significantly (P<0.001) lower in diabetes mellitus than those of control group.

Conclusion: From this study, it may be concluded that diabetic patients are prone to develop coagulation impairment.

Bangladesh Soc Physiol. 2015, June; 10(1): 26-29

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Author Biography

Fayeza Karim, Assistant professor, Department of Physiology, Aichi Medical College, Uttara, Dhaka



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Published

2015-08-21

How to Cite

Karim, F., Akter, Q. S., Jahan, S., Khanom, A., Haque, S., Yeasmin, T., Siddika, T., & Sinha, S. (2015). Coagulation Impairment in Type 2 Diabetes Mellitus. Journal of Bangladesh Society of Physiologist, 10(1), 26–29. https://doi.org/10.3329/jbsp.v10i1.24614

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