Biological studies concerning the antioxidant and antimicrobial activities of Pelargonium species cultivated in Egypt (Family-Geraniaceae)

Authors

  • Abdel Nasser Badawy Singab Faculty of Pharmacy Pharmacognosy Department Ain Shams University, Cairo
  • Hala Mohamed El-Hefnawy Pharmacognosy Department Faculty of Pharmacy Cairo University, Giza
  • Dalia Galal El-Kolobby Pharmacognosy Department Faculty of Pharmacy October 6 University, Giza

DOI:

https://doi.org/10.3329/icpj.v4i2.21481

Keywords:

antimicrobial, antioxidant, DPPH, P. x fragrans, P. peltatum, Geraniaceae

Abstract

Plant-derived pharmaceuticals have become prominent in the market place, making it a favored healthcare choice. In this study, air dried samples of aerial parts of Pelargonium X fragrans Willd. and Pelargonium peltatum LHérit. were separately extracted using successive extraction with a soxhlet apparatus. Each extract was tested for its antimicrobial activity using two Gram-negative bacterial strains (Pseudomonas aeruginosa and Escherichia coli), two Gram-positive bacterial strains (Bacillus subtillus and Staphyllococcus aureus), and clinical fungal isolates (Aspergillus niger and Candida albicans). Also, their antioxidant activity was tested using a DPPH free radical assay. The ethyl acetate, n-Butanol and the total extracts showed moderate activity against the tested microorganisms with significant high activity against E. coli. The free radical scavenging property was found to be in a concentration dependent manner in all the tested fractions. The most effective antioxidant fractions in both spp. was the n-Butanol fraction (85% and 85.2%) at the concentration of 0.375µg/ml followed by the total ethanolic extracts (78.1% and 84.62%), respectively, with the same concentration compared to the standard reference ascorbic acid which showed a significant radicals scavenging potential (79.1%) in the concentration of 1µg/ml.

DOI: http://dx.doi.org/10.3329/icpj.v4i2.21481

International Current Pharmaceutical Journal, January 2015, 4(2): 340-342

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Published

2015-01-07

How to Cite

Singab, A. N. B., El-Hefnawy, H. M., & El-Kolobby, D. G. (2015). Biological studies concerning the antioxidant and antimicrobial activities of Pelargonium species cultivated in Egypt (Family-Geraniaceae). International Current Pharmaceutical Journal, 4(2), 340–342. https://doi.org/10.3329/icpj.v4i2.21481

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Section

Original Articles