Spectrophotometric determination of chlorpheniramine maleate and phenylpropanolamine hydrochloride in dosage forms

Authors

  • Arun Kaura University Institute of Pharmacy Baba Farid University of Health Sciences Faridkot, Punjab
  • Vikas Gupta University Institute of Pharmacy Baba Farid University of Health Sciences Faridkot, Punjab
  • G S Roy B.I.S. College of Pharmacy Gagra, Moga, Punjab
  • Monika Kaura B.I.S. College of Pharmacy Gagra, Moga, Punjab

Keywords:

Derivative, UV absorption, spectral overlap, principle maxima, wavelength range, analytical signal

Abstract

A rapid and simple method for simultaneous determination of Chlorpheniramine Maleate (CPM) and Phenylpropanolamine Hydrochloride (PPM) by first derivative UV spectrophotometry has been developed in combined pharmaceutical dosage forms. The proposed method was successfully applied for the determination of drugs in physical mixture and commercial formulations and results showed good linearity, precision and reproducibility.

DOI: http://dx.doi.org/10.3329/icpj.v2i5.14436

International Current Pharmaceutical Journal, April 2013, 2(5): 97-100

 

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Published

2013-04-04

How to Cite

Spectrophotometric determination of chlorpheniramine maleate and phenylpropanolamine hydrochloride in dosage forms. (2013). International Current Pharmaceutical Journal, 2(5), 97-100. https://doi.org/10.3329/icpj.v2i5.14436

Issue

Vol. 2 No. 5 (2013)

Section

Original Articles

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How to Cite

Spectrophotometric determination of chlorpheniramine maleate and phenylpropanolamine hydrochloride in dosage forms. (2013). International Current Pharmaceutical Journal, 2(5), 97-100. https://doi.org/10.3329/icpj.v2i5.14436