Phytochemical and pharmacological evaluation of Tragia cannabina for anti-inflammatory activity

Authors

  • Raju Venkategowda Hosahally Department of Pharmacognosy, Visveswarapura Institute of Pharmaceutical Sciences, Bangalore, Karnataka
  • Ganapaty Seru Department of Pharmaceutical Sciences, Andhra University, Vishakapatnam
  • Prasanna Shankarrao Sutar
  • Vijaya Gopalachar Joshi Department of Pharmacognosy, Maratha Mandal?s College of Pharmacy, Belgaum-590016, Karnataka
  • Kishori Prasanna Sutar Department of Pharmacognosy, Maratha Mandal?s College of Pharmacy, Belgaum-590016, Karnataka
  • Asif Abdulrahiman Karigar Department of Pharmacognosy, Maratha Mandal?s College of Pharmacy, Belgaum-590016, Karnataka

DOI:

https://doi.org/10.3329/icpj.v1i8.11253

Keywords:

Methanolic extract, chloroform extract, anti-inflammatory activity, carrageenan, Ibuprofen, Euphorbiaceae

Abstract

The present study investigates the anti-inflammatory activity of methanolic and chloroform extracts of Tragia cannabina. The whole plant of Tragia cannabina was extracted with methanol and chloroform by using soxhlet apparatus. The effect of both extracts of Tragia cannabina was studied on carrageenan induced paw edema. The methanolic extract decreased the edema induced in hind paw. The percentage inhibition of paw edema was maximum with methanolic and chloroform extracts of Tragia cannabina at 300mg/kg body weight and has showed significant anti-inflammatory activity. It has been concluded that both the methanolic and chloroform extracts of Tragia cannabina showed significant anti-inflammatory activity comparable to that of reference standard Ibuprofen.

DOI: http://dx.doi.org/10.3329/icpj.v1i8.11253

International Current Pharmaceutical Journal 2012, 1(8): 213-216

 

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Published

2012-07-05

How to Cite

Hosahally, R. V., Seru, G., Sutar, P. S., Joshi, V. G., Sutar, K. P., & Karigar, A. A. (2012). Phytochemical and pharmacological evaluation of Tragia cannabina for anti-inflammatory activity. International Current Pharmaceutical Journal, 1(8), 213–216. https://doi.org/10.3329/icpj.v1i8.11253

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Section

Original Articles