Aetiology and Clinical Presentation of Pancytopenia in a Teaching Hospital


  • ATM Ataur Rahman Assistant professor, Department of Gastroenterology, Faridpur Medical College, Faridpur.
  • ARM Saifuddin Ekram Professor, Department of Medicine, Rajshahi Medical College, Rajshahi
  • Mohammed Shahadat Hossain Assistant Professor, Department of Medicine, OSD, DGHS, Dhaka, attached to Faridpur Medical College, Faridpur
  • Jayanta Kumar Saha Senior Consultant (Medicine), Shahid Tajuddin Ahmed Medical College Hospital, Gazipur
  • Fahreen Rahman 500 bedded Mugda General Hospital, Dhaka.
  • Muhammad Kamruzzaman Assistant Professor (CC) of Haematology, Faridpur Medical College, Faridpur.
  • Ahmed Manadir Hossain Assistant Professor, Department of Medicine, Faridpur Medical College, Faridpur
  • MM Shahin Ul Islam Associate Professor (CC), Department of Gastroenterology, Faridpur Medical College, Faridpur



Pancytopenia, Aplastic anaemia, Hypersplenism, Acute leukemia


Pancytopenia is a morphological description of the peripheral blood picture irrespective of its cause & it denotes simultaneous presence of anaemia, leucopenia and thrombocytopenia. The study was done to observe the demographic profile & the clinical presentations of pancytopenic patients and to find out the aetiology of pancytopenia. This cross sectional study was carried out in Medicine ward of Rajshahi Medical College Hospital from August 2005 to July 2006. A uniform protocol was followed in all cases, to have appropriate history, physical findings & laboratory investigations. The commonest cause of pancytopenia was aplastic anaemia (48%) which was followed by hypersplenism (22%) & acute leukemia (16%). The majority cases of aplastic anaemia were idiopathic (57.69%), only 42.31% cases were due to secondary causes. The majority (94%) of patients was in the age range of 14-60 years and up to 54% was in the age group of 20-40 years. The ratio of male to female in patients of pancytopenia was 1.5:1 and 3:1 in aplastic anaemia. In secondary causes of aplastic anaemia, insecticides and viral hepatitis was found to be causative agent in 45.45% cases of each followed by pregnancy in 9.10% of cases. The common presenting complains of aplastic anaemia were generalized weakness (100%), gum bleeding (76.92%), fever (76.92%) and pallor (96.15%).

Faridpur Med. Coll. J. Jul 2018;13(2): 62-65


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How to Cite

Rahman, A. A., Ekram, A. S., Hossain, M. S., Saha, J. K., Rahman, F., Kamruzzaman, M., Hossain, A. M., & Islam, M. S. U. (2019). Aetiology and Clinical Presentation of Pancytopenia in a Teaching Hospital. Faridpur Medical College Journal, 13(2), 62–65.



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