Intravenous Iron Treatment in Pregnancy: Ferric Carboxymaltose for Correction of Iron Deficiency Anaemia

  • Dilruba Zeba Assoc. Professor, Department of Gynae and Obstetrics, Faridpur Medical College, Faridpur
  • Parvin Akter Khanam Principal Research officer, BIRDEM, Dhaka
  • Mansur Ahamed Senior Product Officer, UniHealth Pharmaceutical Limited, Dhaka
  • Md Abul Khair Assistant Professor, Department of Urology, Faridpur Medical College, Faridpur
Keywords: Iron Deficiency Anaemia, Infusion Ferric Carboxy maltose, Pregnancy, Haemoglobin, Serum Ferritin

Abstract

Iron deficiency is the most common nutritional deficiency state of women in childbearing age. Peri-partum iron deficiency anaemia (IDA) is associated with significant maternal, fetal and infant morbidity. An effective management is needed to prevent adverse outcomes. Current options for treatment are limited; these include oral iron supplements, which are usually ineffective and poorly tolerated, and whole blood transfusion, which carries an inherent risk, should be avoided during pregnancy. Intravenous ferric carboxymaltose is a new treatment option and it is better tolerated with a good result. The study was designed to assess the safety and efficacy of intravenous ferric carboxymaltose for correction of IDA in pregnant women in third trimester. It was a prospective study; 260 anaemic pregnant women received Injection ferric carboxymaltose, as a total dose of 500-1000 mg between 28 to 36 weeks of pregnancy. Safety was assessed by analyzing adverse drug reactions. Ferric carboxy maltose significantly increased Hb level (p<0.001) in all women in this study group. Increased Hb value was observed 3-4 weeks after infusion. None of the women felt worse. No serious adverse effects were found and minor side effects occurred in 34(13%) patients.Our study revealed that the Hb level increased significantly, was well tolerated and without significant side effects.

Faridpur Med. Coll. J. Jul 2017;12(2): 54-57

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Abstract
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5697
Published
2017-10-09
How to Cite
Zeba, D., Khanam, P., Ahamed, M., & Khair, M. A. (2017). Intravenous Iron Treatment in Pregnancy: Ferric Carboxymaltose for Correction of Iron Deficiency Anaemia. Faridpur Medical College Journal, 12(2), 54-57. https://doi.org/10.3329/fmcj.v12i2.34228
Section
Original Articles