TY - JOUR AU - Rima, Rezoana AU - Mamun, Mohammad Abdullah Al PY - 2019/10/03 Y2 - 2024/03/29 TI - Characteristics of Children Hospitalized with Infective Endocarditis at Dhaka Shishu Hospital JF - Cardiovascular Journal JA - Cardiovasc. j. VL - 12 IS - 1 SE - Original Articles DO - 10.3329/cardio.v12i1.43417 UR - https://www.banglajol.info/index.php/CARDIO/article/view/43417 SP - 33-39 AB - <p><strong>Background: </strong>The characteristics of infective endocarditis (IE) have significantly changed in pediatric age group during last few decades. The present study was conducted to study the clinical &amp; lab profile, risk factors, site of cardiac involvement and outcome of infective endocarditis in the largest children hospital of Bangladesh.</p><p><strong>Methods: </strong>This prospective cross-sectional study was conducted in cardiology department with a diagnosis of IE from February 2014 to August 2016. Twenty- four children fulfilled the modified Duke diagnostic criteria.</p><p><strong>Results: </strong>Definite IE was found in 58% (14/24) patients, while the rest had possible IE. The most common presenting symptom was prolonged fever (&gt; 2 weeks) &amp; heart murmur. Most commonly encountered risk factors included congenital heart disease (54%), most commonly ventricular septal defect (21%). Two patients (8.3%) had history of rheumatic heart disease. Other important risk factors include post cardiac surgery (16.7%), prolonged ICU stay of neonates (20.8%). Nineteen patients (79%) were classified as having culture-negative endocarditis and five (21%) as culture positive. The most frequently isolated organisms were streptococci and followed by staphylococci and candida. Fifteen (62.5%) patients had right-sided cardiac involvement. Seven (29%) patients died of endocarditis or its complications.</p><p><strong>Conclusion: </strong>Clinicians should have a high index of suspicion of endocarditis in persistently febrile patients with congenital heart disease and send blood cultures or refer appropriately before prescribing antibiotics.</p><p>Cardiovasc. j. 2019; 12(1): 33-39</p> ER -