Analgesic and Antidiarrheal Activities of Leaf of Podocarpus neriifolius D. Don

Authors

  • Md Rahatullah Razan Phytochemical Research Laboratory, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka-1000
  • Muhammed Mahfuzur Rahman Department of Pharmacy, State University of Bangladesh, Dhaka-1205
  • Faiza Tahia
  • Md Khalid Hossain Phytochemical Research Laboratory, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka-1000
  • Mohammad A Rashid Phytochemical Research Laboratory, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka-1000

DOI:

https://doi.org/10.3329/bpj.v19i2.29283

Keywords:

Analgesic activity, castor oil, diarrhea

Abstract

The methanol extract of leaf of Podocarpus neriifolius D. Don exhibited in vivo peripheral analgesic and antidiarrheal activities in Swiss Albino mice. In the peripheral analgesic activity assay, the methanolic extract showed 50.00 ± 8.57% and 70.25 ± 1.18% inhibition of acetic acid-induced writhing at 200 and 400 mg/kg body weight, respectively. In addition, the extract also revealed a dose dependant inhibition of castor oil- induced diarrhea with 43.77 ± 3.13% and 56.23 ± 6.49% inhibition of feces at 200 and 400 mg/kg body weight, respectively

Bangladesh Pharmaceutical Journal 19(2): 215-218, 2016

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Author Biography

Md Rahatullah Razan, Phytochemical Research Laboratory, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka-1000



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Published

2016-08-12

How to Cite

Razan, M. R., Rahman, M. M., Tahia, F., Hossain, M. K., & Rashid, M. A. (2016). Analgesic and Antidiarrheal Activities of Leaf of Podocarpus neriifolius D. Don. Bangladesh Pharmaceutical Journal, 19(2), 215–218. https://doi.org/10.3329/bpj.v19i2.29283

Issue

Vol. 19 No. 2 (2016)

Section

Articles