Role of red cell distribution width (RDW) in the detection of iron deficiency anaemia in pregnancy within the first 20 weeks of gestation

Authors

  • GS Sultana Department of Clinical Pathology, Clinical Biochemistry and Haematology, BIRDEM, Dhaka
  • SA Haque Department of Thoracic Surgery, CMCH, Chittagong
  • T Sultana Department of Clinical Pathology, BSMMU, Dhaka
  • Q Rahman Department of Clinical Pathology, BSMMU, Dhaka
  • ANN Ahmed Department of Clinical Pathology, BSMMU, Dhaka

DOI:

https://doi.org/10.3329/bmrcb.v37i3.9122

Keywords:

Role, red cell distribution width (RDW), detection, iron deficiency anaemia, pregnancy, first 20 weeks of gestation

Abstract

Iron deficiency anemia is common problem during pregnancy. Red cell size variation (anisocytosis) is the earliest morphologic changes in iron deficiency anemia. Red cell distribution width is a quantitative measure of red cell size variation and it can give the idea of early iron deficiency before other test to become positive.190 pregnant women were included in this study. Red cell distribution width was compared between iron deficient & non-iron deficient pregnant women. Red cell distribution width also compared with Hb level, mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration and peripheral blood film in prelatent iron deficiency, latent iron deficiency, mild and moderate iron deficiency anemia. Red cell distribution width had sensitivity 82.3% and specificity 97.4%. Whereas Hb level, mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration and peripheral blood film all had 56.6%, 29.2%, 68.1%, 15% and 38.9% sensitivity but specificity was 90.9%, 98.7%, 83.1%, 96.1% and 98.7% in the detection of iron deficiency. Red cell distribution width appears to be a reliable and useful parameter for detection of iron deficiency during pregnancy.

DOI: http://dx.doi.org/10.3329/bmrcb.v37i3.9122

BMRCB 2011; 37(3): 102-105

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How to Cite

Sultana, G., Haque, S., Sultana, T., Rahman, Q., & Ahmed, A. (2011). Role of red cell distribution width (RDW) in the detection of iron deficiency anaemia in pregnancy within the first 20 weeks of gestation. Bangladesh Medical Research Council Bulletin, 37(3), 102–105. https://doi.org/10.3329/bmrcb.v37i3.9122

Issue

Vol. 37 No. 3 (2011)

Section

Research Papers

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