Risk Factors for Post-Stroke Depression: A Comparative Study

Authors

  • Mohammad Ibrahim Khalil Department of Neurology, Block-12, Shaheed Suhrawardy Medical College & Hospital Sher-E-Bangla Nagor, Dhaka-1207, Bangladesh
  • Narayan Chandra Kundu Department of Neurology, Shaheed Suhrawardy Medical College & Hospital Sher-E-Bangla Nagor, Dhaka.
  • K M Nazmul Islam Joy Department of Neurology, Shaheed Suhrawardy Medical College & Hospital Sher-E-Bangla Nagor, Dhaka.
  • Rajesh Saha Department of Neurology, Shaheed Suhrawardy Medical College & Hospital Sher-E-Bangla Nagor, Dhaka.
  • Sheikh Md Abul Fazal Department of Neurology, Shaheed Suhrawardy Medical College & Hospital, Sher-E-Bangla Nagor, Dhaka

DOI:

https://doi.org/10.3329/bmrcb.v50i3.78118

Keywords:

Post-stroke depression, risk factors, logistic regression

Abstract

Background: Post-stroke depression (PSD) is one of the common emotional disorders associated with increased morbidity, mortality and strongest predictors for poor quality of life among stroke survivors.

Aims: To find out the frequency and risk factors for PSD.  

Methods: A cross-sectional study, comparing stroke patients with and without depression, whoever was attending for follow up of three to twelve months’ post-stroke duration. The cases were divided into two groups: depression and non-depression according to DSM-V criteria for major depressive disorder. Disability was measured using modified Rankin scale (score 0 complete recovery, 5 worst). Logistic regression was performed to identify risk factors for depression.

Results: A total of 258 stroke cases were recruited and 95 (36.8%) had depression. Mean (SD) age of depressed and non-depressed cases were 57.97(12.64) and 58.1(15.1) years respectively. Logistic regression indicated that ischemic stroke [OR 2.03, 95% CI (1.00-4.11), p= 0.049], disability [OR 4.69, 95% CI (1.09 - 20.16), p = 0.038] and left cerebral hemisphere lesion [OR 4.86, 95% CI (1.19-15.95), p= 0.011] were the important risk factors for post stroke depression.

Conclusions: In this study, we observed that nearly one-third stroke survivors had depression. Ischemic stroke type, having disability and left cerebral hemisphere lesion had strongest associations for the development of this depression. Future studies should explore the relationship for targeted prevention and treatment strategies.

Bangladesh Med Res Counc Bull 2024; 50: 127-134

Downloads

Download data is not yet available.
Abstract
78
PDF
73

Downloads

Published

2024-12-01

How to Cite

Khalil, M. I., Kundu, N. C., Joy, K. M. N. I., Saha, R., & Abul Fazal, S. M. (2024). Risk Factors for Post-Stroke Depression: A Comparative Study. Bangladesh Medical Research Council Bulletin, 50(3), 127–134. https://doi.org/10.3329/bmrcb.v50i3.78118

Issue

Vol. 50 No. 3 (2024)

Section

Research Papers

License

Copyright (c) 2024 Mohammad Ibrahim Khalil, Narayan Chandra Kundu, K M Nazmul Islam Joy, Rajesh Saha

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors who publish with this journal agree to the following terms.

Authors retain copyright and grant the journal right of first publication.

Creative Commons Licence
Articles in the Bangladesh Medical Research Council Bulletin are licensed under a Creative Commons Attribution 4.0 International License (CC-BY) that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).